Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 2905079..2905598 Replicon chromosome
Accession NZ_CP045456
Organism Brevundimonas sp. Bb-A

Toxin (Protein)


Gene name stbE Uniprot ID -
Locus tag BSP_RS14285 Protein ID WP_152950772.1
Coordinates 2905314..2905598 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BSP_RS14280 Protein ID WP_152950771.1
Coordinates 2905079..2905324 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSP_RS14260 2900974..2901249 - 276 WP_152950767.1 DUF2849 domain-containing protein -
BSP_RS14265 2901246..2902631 - 1386 WP_152950768.1 siroheme synthase CysG -
BSP_RS14270 2902754..2903683 + 930 WP_152950769.1 transcriptional regulator GcvA -
BSP_RS14275 2903734..2905035 + 1302 WP_152950770.1 adenylosuccinate lyase -
BSP_RS14280 2905079..2905324 + 246 WP_152950771.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
BSP_RS14285 2905314..2905598 + 285 WP_152950772.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BSP_RS14290 2905595..2906098 + 504 WP_152950773.1 DNA-deoxyinosine glycosylase -
BSP_RS14295 2906098..2906940 + 843 WP_152950774.1 formyltetrahydrofolate deformylase -
BSP_RS14300 2907046..2907672 + 627 WP_054766399.1 fasciclin domain-containing protein -
BSP_RS14305 2907854..2908177 - 324 WP_054767022.1 DUF1476 domain-containing protein -
BSP_RS14310 2908455..2909213 + 759 WP_054766400.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
BSP_RS14315 2909213..2909416 + 204 WP_152950775.1 hypothetical protein -
BSP_RS14320 2909416..2909700 + 285 WP_054766402.1 hypothetical protein -
BSP_RS14325 2909700..2909936 + 237 WP_152950776.1 phosphoribosylformylglycinamidine synthase subunit PurS -
BSP_RS14330 2910033..2910512 + 480 WP_054766404.1 YbhB/YbcL family Raf kinase inhibitor-like protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-71)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11070.88 Da        Isoelectric Point: 10.4934

>T141854 WP_152950772.1 NZ_CP045456:2905314-2905598 [Brevundimonas sp. Bb-A]
MPFDLQFLPSALKEWEKLGAPVRVQFKEKLAERLESPRVPKDALHGMRDHYKIKLRYAGYRLVYRVEDAIITVTVVAVGR
RDRSQVYRDAARRE

Download         Length: 285 bp

>T141854 NZ_CP060122:4244971-4245885 [Sphingobium yanoikuyae]
ATGAGCCGGCCGCCGAAGAACATGGCGATCTCGGTGCGTGATCGCCTGACGGCGCGCGCCCGCGAGCGTCGGGAAAACGC
ACAGCTGCTGATGACCCGCTATGTCATCGAACGCCTGTTGTTTCGTCTCAGCCTGTCGCCACATCGCGAGCGGTTCGTGC
TCAAGGGCGCGATGCTGTTCAGCCTGTGGGCGGCAGCCCCCTATCGCGCCACGGGCGACCTCGATCTGCTCGGCATGGGG
GAAAACGCGCCCGAGCAGCTCGCGGCGGTTTTTCAGGAAATCCTTGGCGTCGCGGTCGATGATGACGGCATCGTGTTCCG
GCCCGAAACCCTGCGCGCGGCTGCGGCCCGTGCCGAGGATGAATATGCCGGCGTCCGTATCGACTTCGTCGCCGAACTCG
CCGGCGCGCGGCTGCCGATGCACGTCGATATCGGCTATGGCGACGCGATCTCGCCGGGCGCGATCGAGATCGAGTATCCG
TCGCTACTCGGCCAGCCCACCGCGCATCTTCGGGCCTATCCGCCCGAAACTGTGGTGGCCGAGAAATTCCAGGCCATGGT
CGCGCTCGGCATGCTGAACACGCGCCTGAAGGATTTCTACGACATCTGGGCGATCGCGGGATCGTTCGCGTTCGATGGCA
CCGTGCTGTCGCGCGCTATCCAGGCGACCTTCGATCGCCGCCAAACCCCGTTGCCCGTCGAGACGCCCCCAGCGCTCACG
CCCGCCTTCGCCGACGAAAAGCAGGGCCAATGGACAGCGTTCCTGCGGCGGACCGAAATCGCGTTGGCGCCCGAACCGTT
CGCGGCAATCCAGGCGCAAATCGCGTCGCTCGTGATGCCGCCGGTGCTGGCGCTCGGCCAAGGCACCGCCTTGGCCAGCG
ACTGGCCCATTGGCGGTCCCTGGAAGGAGAGGTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8843.14 Da        Isoelectric Point: 4.4865

>AT141854 WP_152950771.1 NZ_CP045456:2905079-2905324 [Brevundimonas sp. Bb-A]
MQRVEASVAVSVSDLKKSPSAVMDDAAGQTVAVLNHNRVMAYMVPAAVYEAMVERLDDLALIETVRQRQDETPVRVSLDA
L

Download         Length: 246 bp

>AT141854 NZ_CP060122:4244366-4244974 [Sphingobium yanoikuyae]
ATGGAACCGACGACTCATCGACAACGGGCCCTGGAGGTCGTTCGGCACCGCGGCATAGCGCGTGGACGCGATTTCGACGC
GGCCGGCGTCACGCGGGCGACCCTGCAAAGGCTGCGCGATGAAGGCGTCCTCCAACAGGTCGGCCGCGGTCTCTACAAGC
TGGCCGATGCTGACCTCGACAGCGCGACGAGTCTGGCCGAGGCCGTGCGCATCCAGCCACGCGGCATCATCTGCCTGCTC
TCGGCGCTGCAGTTCCATGAGCTGACCACGCAGACGCCCCACGCAGTGTGGATGATGCTCGGCCAAAAGGACTGGGCACC
GGTCAATCCGTCCGTGGCGCTGAAGATCGTTCGCGCGAGCGGCGAAGCTCTGACGGCGGGCGTGGAGACGCACCTCATCG
ACGGCGTTCCCGTGCCCATCACCGTACCGGCCAAGACCGTCGCCGACTGCTTCAAGCACCGCAACAAGATCGGTATCGAC
GTGGCGGTCGAAGCCCTGCGCGATTTCATGAAATCCCGACCCCGGCCGGACCTAAATGCGATCTACCGTTATGCCCAGCT
CGATCGGGTCCAATCGGTGATCCGGCCCTATCTCGAAGCCATGACATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References