Detailed information of TA system TA141854

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbE-relB/ParE-YafN
• Location: 2905079..2905598
• Replicon: chromosome
• Accession: NZ_CP045456
• Organism: Brevundimonas sp. Bb-A

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: -
• Locus tag: BSP_RS14285
• Protein ID: WP_152950772.1
• Coordinates: 2905314..2905598 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: BSP_RS14280
• Protein ID: WP_152950771.1
• Coordinates: 2905079..2905324 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BSP_RS14260	2900974..2901249	-	276	WP_152950767.1	DUF2849 domain-containing protein	-
BSP_RS14265	2901246..2902631	-	1386	WP_152950768.1	siroheme synthase CysG	-
BSP_RS14270	2902754..2903683	+	930	WP_152950769.1	transcriptional regulator GcvA	-
BSP_RS14275	2903734..2905035	+	1302	WP_152950770.1	adenylosuccinate lyase	-
BSP_RS14280	2905079..2905324	+	246	WP_152950771.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
BSP_RS14285	2905314..2905598	+	285	WP_152950772.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BSP_RS14290	2905595..2906098	+	504	WP_152950773.1	DNA-deoxyinosine glycosylase	-
BSP_RS14295	2906098..2906940	+	843	WP_152950774.1	formyltetrahydrofolate deformylase	-
BSP_RS14300	2907046..2907672	+	627	WP_054766399.1	fasciclin domain-containing protein	-
BSP_RS14305	2907854..2908177	-	324	WP_054767022.1	DUF1476 domain-containing protein	-
BSP_RS14310	2908455..2909213	+	759	WP_054766400.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
BSP_RS14315	2909213..2909416	+	204	WP_152950775.1	hypothetical protein	-
BSP_RS14320	2909416..2909700	+	285	WP_054766402.1	hypothetical protein	-
BSP_RS14325	2909700..2909936	+	237	WP_152950776.1	phosphoribosylformylglycinamidine synthase subunit PurS	-
BSP_RS14330	2910033..2910512	+	480	WP_054766404.1	YbhB/YbcL family Raf kinase inhibitor-like protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-87)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-71)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 11070.88 Da
• Isoelectric Point: 10.4934

>T141854 WP_152950772.1 NZ_CP045456:2905314-2905598 [Brevundimonas sp. Bb-A]
MPFDLQFLPSALKEWEKLGAPVRVQFKEKLAERLESPRVPKDALHGMRDHYKIKLRYAGYRLVYRVEDAIITVTVVAVGR
RDRSQVYRDAARRE

Nucleotide

• Length: 285 bp

>T141854 NZ_CP060122:4244971-4245885 [Sphingobium yanoikuyae]
ATGAGCCGGCCGCCGAAGAACATGGCGATCTCGGTGCGTGATCGCCTGACGGCGCGCGCCCGCGAGCGTCGGGAAAACGC
ACAGCTGCTGATGACCCGCTATGTCATCGAACGCCTGTTGTTTCGTCTCAGCCTGTCGCCACATCGCGAGCGGTTCGTGC
TCAAGGGCGCGATGCTGTTCAGCCTGTGGGCGGCAGCCCCCTATCGCGCCACGGGCGACCTCGATCTGCTCGGCATGGGG
GAAAACGCGCCCGAGCAGCTCGCGGCGGTTTTTCAGGAAATCCTTGGCGTCGCGGTCGATGATGACGGCATCGTGTTCCG
GCCCGAAACCCTGCGCGCGGCTGCGGCCCGTGCCGAGGATGAATATGCCGGCGTCCGTATCGACTTCGTCGCCGAACTCG
CCGGCGCGCGGCTGCCGATGCACGTCGATATCGGCTATGGCGACGCGATCTCGCCGGGCGCGATCGAGATCGAGTATCCG
TCGCTACTCGGCCAGCCCACCGCGCATCTTCGGGCCTATCCGCCCGAAACTGTGGTGGCCGAGAAATTCCAGGCCATGGT
CGCGCTCGGCATGCTGAACACGCGCCTGAAGGATTTCTACGACATCTGGGCGATCGCGGGATCGTTCGCGTTCGATGGCA
CCGTGCTGTCGCGCGCTATCCAGGCGACCTTCGATCGCCGCCAAACCCCGTTGCCCGTCGAGACGCCCCCAGCGCTCACG
CCCGCCTTCGCCGACGAAAAGCAGGGCCAATGGACAGCGTTCCTGCGGCGGACCGAAATCGCGTTGGCGCCCGAACCGTT
CGCGGCAATCCAGGCGCAAATCGCGTCGCTCGTGATGCCGCCGGTGCTGGCGCTCGGCCAAGGCACCGCCTTGGCCAGCG
ACTGGCCCATTGGCGGTCCCTGGAAGGAGAGGTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8843.14 Da
• Isoelectric Point: 4.4865

>AT141854 WP_152950771.1 NZ_CP045456:2905079-2905324 [Brevundimonas sp. Bb-A]
MQRVEASVAVSVSDLKKSPSAVMDDAAGQTVAVLNHNRVMAYMVPAAVYEAMVERLDDLALIETVRQRQDETPVRVSLDA
L

Nucleotide

• Length: 246 bp

>AT141854 NZ_CP060122:4244366-4244974 [Sphingobium yanoikuyae]
ATGGAACCGACGACTCATCGACAACGGGCCCTGGAGGTCGTTCGGCACCGCGGCATAGCGCGTGGACGCGATTTCGACGC
GGCCGGCGTCACGCGGGCGACCCTGCAAAGGCTGCGCGATGAAGGCGTCCTCCAACAGGTCGGCCGCGGTCTCTACAAGC
TGGCCGATGCTGACCTCGACAGCGCGACGAGTCTGGCCGAGGCCGTGCGCATCCAGCCACGCGGCATCATCTGCCTGCTC
TCGGCGCTGCAGTTCCATGAGCTGACCACGCAGACGCCCCACGCAGTGTGGATGATGCTCGGCCAAAAGGACTGGGCACC
GGTCAATCCGTCCGTGGCGCTGAAGATCGTTCGCGCGAGCGGCGAAGCTCTGACGGCGGGCGTGGAGACGCACCTCATCG
ACGGCGTTCCCGTGCCCATCACCGTACCGGCCAAGACCGTCGCCGACTGCTTCAAGCACCGCAACAAGATCGGTATCGAC
GTGGCGGTCGAAGCCCTGCGCGATTTCATGAAATCCCGACCCCGGCCGGACCTAAATGCGATCTACCGTTATGCCCAGCT
CGATCGGGTCCAATCGGTGATCCGGCCCTATCTCGAAGCCATGACATGA