Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 2408171..2409699 Replicon chromosome
Accession NZ_CP045456
Organism Brevundimonas sp. Bb-A

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag BSP_RS11830 Protein ID WP_152950468.1
Coordinates 2408779..2409699 (+) Length 307 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag BSP_RS11825 Protein ID WP_152950467.1
Coordinates 2408171..2408782 (+) Length 204 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSP_RS11800 2403895..2404788 + 894 WP_152950462.1 hypothetical protein -
BSP_RS11805 2404799..2405683 - 885 WP_152950463.1 nucleotidyltransferase -
BSP_RS11810 2405680..2406183 - 504 WP_152950464.1 HORMA domain containing protein -
BSP_RS11815 2406183..2406653 - 471 WP_152950465.1 hypothetical protein -
BSP_RS11820 2406640..2407521 - 882 WP_152950466.1 AAA family ATPase -
BSP_RS11825 2408171..2408782 + 612 WP_152950467.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
BSP_RS11830 2408779..2409699 + 921 WP_152950468.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
BSP_RS11835 2409746..2410135 - 390 WP_152951135.1 AlpA family phage regulatory protein -
BSP_RS11840 2410383..2410655 - 273 WP_152950469.1 hypothetical protein -
BSP_RS11845 2410652..2411260 - 609 WP_152950470.1 lytic transglycosylase domain-containing protein -
BSP_RS11850 2411254..2411697 - 444 WP_152951136.1 S26 family signal peptidase -
BSP_RS11855 2411763..2412926 - 1164 WP_152950471.1 TrbI/VirB10 family protein -
BSP_RS11860 2412923..2413933 - 1011 WP_152951137.1 TrbG/VirB9 family P-type conjugative transfer protein -
BSP_RS11865 2414008..2414691 - 684 WP_008260103.1 conjugal transfer protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2364843..2411350 46507


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(39-258)

Antitoxin

AbiEi antitoxin C-terminal domain

(60-193)


Sequences

Toxin        


Download         Length: 307 a.a.        Molecular weight: 34409.27 Da        Isoelectric Point: 4.9983

>T141852 WP_152950468.1 NZ_CP045456:2408779-2409699 [Brevundimonas sp. Bb-A]
MTRRPVRNVAASVRDRLTARARLRREDVQLVFLRYAIERLLYRLSVSNHHDRFILKGAMLFAQWAPTPHRPSGDLDLLGL
GDSAPDVVRDIFREVVAIPVDDDGVLFLPDTLVAEIARPDAEYSGVSVDVSAEINGAKLKVHIDIGYGDTITPAAVQIEY
PSLLDQPRAKLLAYPRETVVAEKFQAMVELGMANTRLKDFFDLWAIANTFEFDGETLAEAFARTFDRRDTALPTSDPLAL
TSAFAERKQKEWTAFLDRTDIVIASKSLPETQALIADFVLPPVLARARNEPFVRRWTPDDGWMETT

Download         Length: 921 bp

>T141852 NZ_CP060122:c3410402-3410001 [Sphingobium yanoikuyae]
ATGTTCCTGCTCGATACCAATATCCTGTCGGACCTGATCCGGCAGCCCGATGGCCTGGTTGCCCGCGCGATTGCCGACGT
GGGTGAAGATGCCATCGCGACCAGCATCATAGTCCCCGGCGAAATGCGCTATGGTGGAGCAAAGCGCGGATCGGCACGCC
TCCAGGGCAAAATCGATCAATTGCTATCCCTGATCCCGGTGTTGCCGCTCAAGAATGATGCCAATGCCAGCTACGGACGT
TTGCGCGCGGAGCTGGAACGGCGGGGAACTCCGATTGGCGCCGACGACATGCTGATCGCCGCGCACGCCTTCGCAGTCGA
CGCTACGCTTGTTACCGACAATATCCGCGAGTTCGAACGCGTCGATGGCCTCAAGCTGGTCAACTGGCTTCGGACGACCT
GA

Antitoxin


Download         Length: 204 a.a.        Molecular weight: 22331.79 Da        Isoelectric Point: 10.4176

>AT141852 WP_152950467.1 NZ_CP045456:2408171-2408782 [Brevundimonas sp. Bb-A]
MATMTHIERALAVAQAQGVARTRDFVTAGVPRVYLKRLVEDGRLSQVGRGLYRPNDVSLPTTSSLAEAARVVPNGVIALL
SALRFHGLTTQAPHAVWLLIGTRAWTPVNPPMRLKIVRASGPSLTEGVETHDIDGVSVPITSPAKTVVDCFKYRRRVGLD
VALEALQDFMKDSAHGRQRDALWRYAEIDRVQTVIRPYLEALS

Download         Length: 612 bp

>AT141852 NZ_CP060122:c3410657-3410406 [Sphingobium yanoikuyae]
ATATGCCAAGGAGTCGCCAAGAACGTCGAACGCCATGTCAAGCTCTTCAAAAACGGCCGTAGTCAGGTGGTCCGCATTCC
GCGCGAGTTCGAGCTTCCCGGAGAGGATGCGATTATCCGCAAGGAAGGCACGCGGCTGATCATCGAGCCCATGCGGCCAC
GCTCGCTTCTGGCTGTTCTCAAGACATGGGAACCGCTCGATGAAGATATTGGTCCAATCGAGGACCTTCCGGCCGAATCC
GTCGATATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References