Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 945358..945982 Replicon chromosome
Accession NZ_CP045456
Organism Brevundimonas sp. Bb-A

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag BSP_RS04660 Protein ID WP_152949457.1
Coordinates 945358..945681 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BSP_RS04665 Protein ID WP_152949458.1
Coordinates 945674..945982 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSP_RS04640 941255..943012 - 1758 WP_152949455.1 hypothetical protein -
BSP_RS04650 943457..943918 - 462 WP_054766821.1 TIGR02300 family protein -
BSP_RS04655 944043..945353 + 1311 WP_152949456.1 3-phosphoshikimate 1-carboxyvinyltransferase -
BSP_RS04660 945358..945681 + 324 WP_152949457.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BSP_RS04665 945674..945982 + 309 WP_152949458.1 putative addiction module antidote protein Antitoxin
BSP_RS04670 945982..946626 + 645 WP_152949459.1 (d)CMP kinase -
BSP_RS04675 946784..948487 + 1704 WP_152949460.1 30S ribosomal protein S1 -
BSP_RS04680 948804..949094 + 291 WP_152949461.1 integration host factor subunit beta -
BSP_RS04685 949120..949536 + 417 WP_152949462.1 large-conductance mechanosensitive channel protein MscL -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(15-104)

Antitoxin

Uncharacterized protein HI1420

(5-94)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12279.98 Da        Isoelectric Point: 10.1283

>T141850 WP_152949457.1 NZ_CP045456:945358-945681 [Brevundimonas sp. Bb-A]
MSPIDDNVATRLTFTPVFDRWLLRLRDQRAVARITTRLQRLSRGQWGDVKPVGEGVSELRIAYGPGYRLYAMKKNEAWVI
LLAGGDKSSQDRDIAEAKRLAEEYRND

Download         Length: 324 bp

>T141850 NZ_CP060122:1896361-1896792 [Sphingobium yanoikuyae]
ATGAGCTTCCTGCTCGACACCAACATCATCTCGGAAGGCGCACGGCCGCGTCCCGATCCCGGCGTGATGGAATGGCTGGC
ATCGATGGATGAGGAAGAGTTGTTCCTGAGCGTCGTATCGGTGGCCGAACTGCGCCATGGGATCGAGCGCATGGACAAGG
GCGCGCGACAGGCGGGCCTCGACATCTGGCTGACCGAGCAACTGGCCCCGCGATTTGAAGACAGACTGCTCTCCATCGAC
AGCGTAACGGCGGACCTGTGGGGCCGGATCGTCGCCCGCGCGCAAGGCGCGGGCCGACCCATCGGCGCGATGGACGCTTT
CATTGCTGCCCATGCCCAGCAGCATCAACTGACACTCGTGACGCGCAATATCTCCGACTTCGAGGCGACCGGCATCCGCC
TCTTCAACCCTTGGACCGAAGGGAAAGCCTGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11197.81 Da        Isoelectric Point: 4.4128

>AT141850 WP_152949458.1 NZ_CP045456:945674-945982 [Brevundimonas sp. Bb-A]
MTEPLIEFDPARYLNTPEAVEEYLVSSFEEAAELGDPRIITNALGVVARAKGMTQMARDAELSRTALYRALSEEGRPELS
TIFKVMQALGLRLAPVRVDSAA

Download         Length: 309 bp

>AT141850 NZ_CP060122:1896095-1896364 [Sphingobium yanoikuyae]
ATGGCGGTTGAAACGCATCCGGATAGCTGGACTGTTGCGCAGGCCAAGGCACGGCTGAGCGAGGTCATCGAAAAGGCGCG
GCGCGAACCCCAGGCGATTACCCGCCACGGCAAGAGCGCCGTCGTCGTGGTGGATGCCGGACTATGGGAACGGGTCCAGC
GCCGCCAGCATCGCGGTAGCTTCGCCGACTTCCTGCTGACCTCGCCGCTGCGCGGATCAGGGCTTGAGGTGGAGCGTCTC
AAGGACGGCGTGCGCGAGATCGATCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References