Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 299148..299744 Replicon chromosome
Accession NZ_CP045451
Organism Enterobacter hormaechei strain 14320055602

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag GEA57_RS01435 Protein ID WP_203436054.1
Coordinates 299442..299744 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A927HL08
Locus tag GEA57_RS01430 Protein ID WP_023295755.1
Coordinates 299148..299435 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GEA57_RS01425 297520..299151 + 1632 WP_003860350.1 Na/Pi cotransporter family protein -
GEA57_RS01430 299148..299435 - 288 WP_023295755.1 putative addiction module antidote protein Antitoxin
GEA57_RS01435 299442..299744 - 303 WP_203436054.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GEA57_RS01440 299942..300814 + 873 WP_003860347.1 23S rRNA pseudouridine(2604) synthase RluF -
GEA57_RS01445 300815..301087 - 273 WP_017382612.1 DUF3811 domain-containing protein -
GEA57_RS01450 301138..302082 - 945 WP_015570166.1 ketopantoate/pantoate/pantothenate transporter PanS -
GEA57_RS01455 302176..303525 - 1350 WP_045344657.1 lysine-sensitive aspartokinase 3 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-93)

Antitoxin

Uncharacterized protein HI1420

(3-90)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11467.28 Da        Isoelectric Point: 9.9669

>T141834 WP_203436054.1 NZ_CP045451:c299744-299442 [Enterobacter hormaechei]
MKEIVQTESFRRWEQNLKDRRAKTIIASRLFRLANGLAGDIRPVGEGISELRIYFGPGYRIYFKDQGNCIIVLLCGGDKS
SQARDILMAKMLSNVSQWQE

Download         Length: 303 bp

>T141834 NZ_CP060121:c1227656-1227549 [Escherichia coli BL21]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10101.59 Da        Isoelectric Point: 5.7807

>AT141834 WP_023295755.1 NZ_CP045451:c299435-299148 [Enterobacter hormaechei]
MHKLTPYDPANALLDDEEIAVFMADALETGDSAYIAKALGVIARAKGMSTISQQTGLSREQLYRSFSDKGNPTLKTTLAV
MKALGLGLTIKPSGD

Download         Length: 288 bp

>AT141834 NZ_CP060121:1227703-1227769 [Escherichia coli BL21]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References