Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3100939..3101580 Replicon chromosome
Accession NZ_CP045428
Organism Acinetobacter baumannii strain AbCAN2

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag F9K57_RS14590 Protein ID WP_159142375.1
Coordinates 3100939..3101328 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag F9K57_RS14595 Protein ID WP_011860336.1
Coordinates 3101335..3101580 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F9K57_RS14575 3096058..3098253 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
F9K57_RS14580 3098441..3099007 - 567 WP_000651536.1 rhombosortase -
F9K57_RS14585 3099085..3100170 - 1086 WP_000049106.1 hypothetical protein -
F9K57_RS14590 3100939..3101328 - 390 WP_159142375.1 hypothetical protein Toxin
F9K57_RS14595 3101335..3101580 - 246 WP_011860336.1 succinate dehydrogenase assembly factor 2 Antitoxin
F9K57_RS14600 3101780..3102952 + 1173 WP_001190546.1 acyl-CoA dehydrogenase family protein -
F9K57_RS14605 3103002..3104492 - 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
F9K57_RS14610 3104672..3105049 - 378 WP_001216380.1 50S ribosomal protein L17 -
F9K57_RS14615 3105068..3106075 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15606.91 Da        Isoelectric Point: 10.3889

>T141786 WP_159142375.1 NZ_CP045428:c3101328-3100939 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVIISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYQSQNTV
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWLDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T141786 NZ_CP060086:c5704619-5704341 [Pseudomonas aeruginosa]
ATGATTCTGACCTTTCGCTGCGACGAGACTCGTCAGCTTTTTGAGACGGGTCTTTCGAGGCGGTGGGGAGCGATCCTCAC
AGTCGCTACGCGTAAGCTCGCAATGCTTCATGCGGCTACGGAGCTTCGAGACTTGCGCTCTCCACCTGGAAACCGGTTGG
AGCCGTTGCAGGGAAAGCGGGCGGGCCAACATAGCATCAGGATCAATGACCAGTGGCGTGTCTGTTTCGTCTGGACGGAT
GCGGGTCCCGAAGAAGTCGAAATAGTTGATTACCACTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9842.27 Da        Isoelectric Point: 4.9001

>AT141786 WP_011860336.1 NZ_CP045428:c3101580-3101335 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Download         Length: 246 bp

>AT141786 NZ_CP060086:c5704329-5704024 [Pseudomonas aeruginosa]
ATGGCTACCAATGGTATGCGCCCCATCCATCCTGGGGAAATATTGCGCGATGAGTTTCTGATGGAGTTGGATATCTCTCC
AGCTGCTCTAGCACGCGCTTTGAAAGTCTCCGCTCCGACAGTGAACGATATCGTTCGTGAGCAGCGTGGTATCTCCGCAG
ATATGGCGATTCGTCTGGGGCGTTACTTTGATACGTCCGCTCAGTTCTGGATGAATCTCCAGAGTGAGTACTCGTTAGCA
ACTGCTTATGCGGCGAATGGCGAGCAGATCGAACATGAGATTGAGCCGCTGCTTGCTCACGGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References