Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 6207722..6208257 Replicon chromosome
Accession NZ_CP045427
Organism Shewanella sp. YLB-09

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag FS418_RS26700 Protein ID WP_142873266.1
Coordinates 6207722..6208006 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FS418_RS26705 Protein ID WP_142873265.1
Coordinates 6208006..6208257 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FS418_RS26680 6203550..6204521 + 972 WP_142873269.1 nucleoside hydrolase -
FS418_RS26685 6204655..6205296 - 642 WP_185965814.1 LysE family translocator -
FS418_RS26690 6206192..6206392 + 201 WP_142873268.1 hypothetical protein -
FS418_RS26695 6206782..6207711 + 930 WP_142873267.1 DUF1186 domain-containing protein -
FS418_RS26700 6207722..6208006 - 285 WP_142873266.1 Txe/YoeB family addiction module toxin Toxin
FS418_RS26705 6208006..6208257 - 252 WP_142873265.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FS418_RS26710 6208632..6208799 - 168 WP_185965803.1 hypothetical protein -
FS418_RS26715 6209004..6209756 + 753 WP_185965802.1 TdeIII family type II restriction endonuclease -
FS418_RS26720 6209784..6211181 - 1398 WP_142873263.1 DNA cytosine methyltransferase -
FS418_RS26725 6211323..6211697 + 375 WP_142873262.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(13-92)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11300.78 Da        Isoelectric Point: 9.7953

>T141784 WP_142873266.1 NZ_CP045427:c6208006-6207722 [Shewanella sp. YLB-09]
MKTNTTTLFSTFYSDQAWNDYLYWQQQDKKTLKRINLLIKDCQRTPFEGIGKPERLKENLSGYWSRRITDEHSLVYKATQ
DRLTIVAVRYHYSS

Download         Length: 285 bp

>T141784 NZ_CP060086:c4997049-4996702 [Pseudomonas aeruginosa]
ATGTCCCCGGTCGTCATTCGTTTTACTGATACCGCAGAGCAAAGCATCGAAGACCAAGTCCACCACTTGGCTCCATTCCA
AGGTGAACAGGCTGCACTCCAGTTAGTACTGAGCCTTTTGGATGAGATTGAAGAGAAGATTTCACTTGCACCTAAAGGTT
ACCCAGTCAGCCAGCAGGCGAGTCTTCTGGGGGTGCTGAGCTATCGCGAGCTTAATACCGGCCCCTATCGTGTTTTTTAC
GAATTCCACGAAGAGCAAGGCGAGGCGGCAGTGATCTTGGTTTTGCGACAGAAGCAGAGCGTTGAGCAGCAATTGATCCG
CTACTGCTTGGTGGGGCCAATCGAGTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9447.56 Da        Isoelectric Point: 4.4341

>AT141784 WP_142873265.1 NZ_CP045427:c6208257-6208006 [Shewanella sp. YLB-09]
MSVYSFTEVRSNLKSVCDSVVNDCEPAVIHRRGAENVVMFSESEFNSWKETIYLLSNPVNAKHLLDSIKQIDDGQAQERE
LLD

Download         Length: 252 bp

>AT141784 NZ_CP060086:c4997310-4997059 [Pseudomonas aeruginosa]
ATGCGAGTCGAGACAATTAGTTATTTGAAACGTCATGCGGCTGACCTGGATTTATCCGAGCCAATGGTCGTCACGCAGAA
CGGTGTTCCTGCCTATGTGGTTGAGTCATATGCTGAGCGGAAGCAGCGCGATGAAGCAATTGCGCTGGTGAAGTTGCTTG
CGATTGGCTCCCGCCAGTACGCAGAAGGCAAGCATCGCTCTGTTGATGATTTGAAAGCTCGCCTTTCCAGGAGGTTCGCT
CAGCCAGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References