Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 4061443..4062309 Replicon chromosome
Accession NZ_CP045427
Organism Shewanella sp. YLB-09

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag FS418_RS17185 Protein ID WP_142874274.1
Coordinates 4061908..4062309 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag FS418_RS17180 Protein ID WP_142874273.1
Coordinates 4061443..4061841 (+) Length 133 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FS418_RS17165 4057671..4059077 - 1407 WP_142874270.1 sulfate adenylyltransferase subunit CysN -
FS418_RS17170 4059159..4059512 - 354 WP_142874271.1 four helix bundle protein -
FS418_RS17175 4059700..4060605 - 906 WP_142874272.1 sulfate adenylyltransferase subunit CysD -
FS418_RS17180 4061443..4061841 + 399 WP_142874273.1 nucleotidyltransferase domain-containing protein Antitoxin
FS418_RS17185 4061908..4062309 + 402 WP_142874274.1 DUF86 domain-containing protein Toxin
FS418_RS17190 4062815..4063372 - 558 WP_142874275.1 hypothetical protein -
FS418_RS17195 4063538..4063897 - 360 Protein_3314 UTP--glucose-1-phosphate uridylyltransferase -
FS418_RS17200 4063910..4064110 + 201 WP_142874276.1 nucleotidyltransferase domain-containing protein -
FS418_RS17205 4064308..4065378 + 1071 WP_142874277.1 dTDP-glucose 4,6-dehydratase -
FS418_RS17210 4065375..4066250 + 876 WP_142874278.1 glucose-1-phosphate thymidylyltransferase RfbA -
FS418_RS17215 4066330..4067217 - 888 WP_142874279.1 UTP--glucose-1-phosphate uridylyltransferase GalU -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(14-129)

Antitoxin

Polymerase beta, nucleotidyltransferase

(11-96)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 15110.32 Da        Isoelectric Point: 6.7496

>T141783 WP_142874274.1 NZ_CP045427:4061908-4062309 [Shewanella sp. YLB-09]
MNDITINKLTTIRRCLTRIKDVYGDGSSFPHDYTLQDSVLLNLQRACEASIDIANHISRQHKFGVPQSSRDSFTLLAQND
VIPVALADKLKKMVGLRNIAVHDYQELNLDIVIHVIKHNLKDFEDFIDAIQPV

Download         Length: 402 bp

>T141783 NZ_CP060086:c4669754-4668999 [Pseudomonas aeruginosa]
GTGAGCGAGATCTGGCGACAGTGCAAGGGTGAGCGGCATGTCCGACCGCTCCAGGGGCGGCTGGTGCGGTTGGTGGAGAG
CCAGGAGCAGGTGGCGACCCTGCAATTGGTCGACACCCTGGAAGAACAGGCGTTGCTCGAGGAACTGCTCGAGTCGAGCA
AGCCGCCGGTGCCGGCGGATGCCGAGCCATTGCATTACCTGTTGAAGACCCCGTTCCGTTATCCGCCCTTGCGTTGGGGG
TCGCGGTTTGGCCGTCGTCACGAGCCAAGCCTGTTCTACGCCGCGTTGAAGCTGGAAACGGCCATGGCCGAAAGCGCGTA
TTACCGTTGTGTCCTGTGGAGTGGCATGGCGGTGCCGCCACCGAGCGGGAGGATTCTGTCCGAGCACGCTTCGTTCGAGG
CGGGCTGGAAGGTGGAGCGGGGAATCCGTCTGCAGGCGCCGCCTTTCTCCGATCACGAGGCTGCGCTGACCGACATCGCC
GACTACCGCGCTCCCCAGGAACTGGGGAGTGCCATGCGCAGCGCCGGGGTGCAGGCATTCGAATACCGTTCGGCGCGTTG
CCCGGAGCGCGGCTGCAATGTCGCCCTGTTCACGCCCGCGGCCTTCACCGAAAAGCGTCCTCGCAACCTGACGCCCTGGC
TGTGCGAAACCACGGCCGGTTACGTGGCCTTCAAGCCGGCGCATGTGCCGGGGTCGCCGAAAATCTTCTCCTGGGAGCTG
TTCCTGGTGGACGGAAAGTTGCCGCATCCGGCGTGA

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14926.91 Da        Isoelectric Point: 4.3168

>AT141783 WP_142874273.1 NZ_CP045427:4061443-4061841 [Shewanella sp. YLB-09]
MFQLDKAVLINAVRSKLPNLKLIYLFGSYASGEQHPESDLDIAILPNKALDNITRWDIAQELASEFDVDVDLIDLNCAST
VLCQQVITQGICLWGNTHDDDIFTTKTMSMYQHLQAERAEILSDFKSINHNQ

Download         Length: 399 bp

>AT141783 NZ_CP060086:c4670257-4669889 [Pseudomonas aeruginosa]
ATGAGCGCTCTCATCAAGGAACGTCCCAGCGCCGATGCTGTCCTGGCCAAGGCCGTCCTGGCCGCGCGCGAGCAATTGGG
GCTGACGCAGCTCGAACTGGCCGGCATCGTCGGCGTCGATCGCAGCGCCATCAGCCGCTGGAAGACCCAGGGCCTGCGGG
TGGACAGCAAGACCGGCGAGCTGGCTCTGCTGCTGGTGCGAGTCTATCGCGCACTGTATGCCCTGTTCGGCGGGCAGCAG
GAGGACATGCGCCACTTCCTGCGCACTCCCAACCATCACCTGGCGGGCGAGCCGCTGGCACTGATGGGACAGGTGCAGGG
CCTGGTTCATGTGCTGGAATACCTCGATGCGATCCGCGGCAAGGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References