Detailed information of TA system
Overview
TA module
| Type | VII | Classification (family/domain) | HepT-MntA/HepT(toxin) |
| Location | 4061443..4062309 | Replicon | chromosome |
| Accession | NZ_CP045427 | ||
| Organism | Shewanella sp. YLB-09 | ||
Toxin (Protein)
| Gene name | hepT | Uniprot ID | - |
| Locus tag | FS418_RS17185 | Protein ID | WP_142874274.1 |
| Coordinates | 4061908..4062309 (+) | Length | 134 a.a. |
Antitoxin (Protein)
| Gene name | mntA | Uniprot ID | - |
| Locus tag | FS418_RS17180 | Protein ID | WP_142874273.1 |
| Coordinates | 4061443..4061841 (+) | Length | 133 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FS418_RS17165 | 4057671..4059077 | - | 1407 | WP_142874270.1 | sulfate adenylyltransferase subunit CysN | - |
| FS418_RS17170 | 4059159..4059512 | - | 354 | WP_142874271.1 | four helix bundle protein | - |
| FS418_RS17175 | 4059700..4060605 | - | 906 | WP_142874272.1 | sulfate adenylyltransferase subunit CysD | - |
| FS418_RS17180 | 4061443..4061841 | + | 399 | WP_142874273.1 | nucleotidyltransferase domain-containing protein | Antitoxin |
| FS418_RS17185 | 4061908..4062309 | + | 402 | WP_142874274.1 | DUF86 domain-containing protein | Toxin |
| FS418_RS17190 | 4062815..4063372 | - | 558 | WP_142874275.1 | hypothetical protein | - |
| FS418_RS17195 | 4063538..4063897 | - | 360 | Protein_3314 | UTP--glucose-1-phosphate uridylyltransferase | - |
| FS418_RS17200 | 4063910..4064110 | + | 201 | WP_142874276.1 | nucleotidyltransferase domain-containing protein | - |
| FS418_RS17205 | 4064308..4065378 | + | 1071 | WP_142874277.1 | dTDP-glucose 4,6-dehydratase | - |
| FS418_RS17210 | 4065375..4066250 | + | 876 | WP_142874278.1 | glucose-1-phosphate thymidylyltransferase RfbA | - |
| FS418_RS17215 | 4066330..4067217 | - | 888 | WP_142874279.1 | UTP--glucose-1-phosphate uridylyltransferase GalU | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 134 a.a. Molecular weight: 15110.32 Da Isoelectric Point: 6.7496
>T141783 WP_142874274.1 NZ_CP045427:4061908-4062309 [Shewanella sp. YLB-09]
MNDITINKLTTIRRCLTRIKDVYGDGSSFPHDYTLQDSVLLNLQRACEASIDIANHISRQHKFGVPQSSRDSFTLLAQND
VIPVALADKLKKMVGLRNIAVHDYQELNLDIVIHVIKHNLKDFEDFIDAIQPV
MNDITINKLTTIRRCLTRIKDVYGDGSSFPHDYTLQDSVLLNLQRACEASIDIANHISRQHKFGVPQSSRDSFTLLAQND
VIPVALADKLKKMVGLRNIAVHDYQELNLDIVIHVIKHNLKDFEDFIDAIQPV
Download Length: 402 bp
>T141783 NZ_CP060086:c4669754-4668999 [Pseudomonas aeruginosa]
GTGAGCGAGATCTGGCGACAGTGCAAGGGTGAGCGGCATGTCCGACCGCTCCAGGGGCGGCTGGTGCGGTTGGTGGAGAG
CCAGGAGCAGGTGGCGACCCTGCAATTGGTCGACACCCTGGAAGAACAGGCGTTGCTCGAGGAACTGCTCGAGTCGAGCA
AGCCGCCGGTGCCGGCGGATGCCGAGCCATTGCATTACCTGTTGAAGACCCCGTTCCGTTATCCGCCCTTGCGTTGGGGG
TCGCGGTTTGGCCGTCGTCACGAGCCAAGCCTGTTCTACGCCGCGTTGAAGCTGGAAACGGCCATGGCCGAAAGCGCGTA
TTACCGTTGTGTCCTGTGGAGTGGCATGGCGGTGCCGCCACCGAGCGGGAGGATTCTGTCCGAGCACGCTTCGTTCGAGG
CGGGCTGGAAGGTGGAGCGGGGAATCCGTCTGCAGGCGCCGCCTTTCTCCGATCACGAGGCTGCGCTGACCGACATCGCC
GACTACCGCGCTCCCCAGGAACTGGGGAGTGCCATGCGCAGCGCCGGGGTGCAGGCATTCGAATACCGTTCGGCGCGTTG
CCCGGAGCGCGGCTGCAATGTCGCCCTGTTCACGCCCGCGGCCTTCACCGAAAAGCGTCCTCGCAACCTGACGCCCTGGC
TGTGCGAAACCACGGCCGGTTACGTGGCCTTCAAGCCGGCGCATGTGCCGGGGTCGCCGAAAATCTTCTCCTGGGAGCTG
TTCCTGGTGGACGGAAAGTTGCCGCATCCGGCGTGA
GTGAGCGAGATCTGGCGACAGTGCAAGGGTGAGCGGCATGTCCGACCGCTCCAGGGGCGGCTGGTGCGGTTGGTGGAGAG
CCAGGAGCAGGTGGCGACCCTGCAATTGGTCGACACCCTGGAAGAACAGGCGTTGCTCGAGGAACTGCTCGAGTCGAGCA
AGCCGCCGGTGCCGGCGGATGCCGAGCCATTGCATTACCTGTTGAAGACCCCGTTCCGTTATCCGCCCTTGCGTTGGGGG
TCGCGGTTTGGCCGTCGTCACGAGCCAAGCCTGTTCTACGCCGCGTTGAAGCTGGAAACGGCCATGGCCGAAAGCGCGTA
TTACCGTTGTGTCCTGTGGAGTGGCATGGCGGTGCCGCCACCGAGCGGGAGGATTCTGTCCGAGCACGCTTCGTTCGAGG
CGGGCTGGAAGGTGGAGCGGGGAATCCGTCTGCAGGCGCCGCCTTTCTCCGATCACGAGGCTGCGCTGACCGACATCGCC
GACTACCGCGCTCCCCAGGAACTGGGGAGTGCCATGCGCAGCGCCGGGGTGCAGGCATTCGAATACCGTTCGGCGCGTTG
CCCGGAGCGCGGCTGCAATGTCGCCCTGTTCACGCCCGCGGCCTTCACCGAAAAGCGTCCTCGCAACCTGACGCCCTGGC
TGTGCGAAACCACGGCCGGTTACGTGGCCTTCAAGCCGGCGCATGTGCCGGGGTCGCCGAAAATCTTCTCCTGGGAGCTG
TTCCTGGTGGACGGAAAGTTGCCGCATCCGGCGTGA
Antitoxin
Download Length: 133 a.a. Molecular weight: 14926.91 Da Isoelectric Point: 4.3168
>AT141783 WP_142874273.1 NZ_CP045427:4061443-4061841 [Shewanella sp. YLB-09]
MFQLDKAVLINAVRSKLPNLKLIYLFGSYASGEQHPESDLDIAILPNKALDNITRWDIAQELASEFDVDVDLIDLNCAST
VLCQQVITQGICLWGNTHDDDIFTTKTMSMYQHLQAERAEILSDFKSINHNQ
MFQLDKAVLINAVRSKLPNLKLIYLFGSYASGEQHPESDLDIAILPNKALDNITRWDIAQELASEFDVDVDLIDLNCAST
VLCQQVITQGICLWGNTHDDDIFTTKTMSMYQHLQAERAEILSDFKSINHNQ
Download Length: 399 bp
>AT141783 NZ_CP060086:c4670257-4669889 [Pseudomonas aeruginosa]
ATGAGCGCTCTCATCAAGGAACGTCCCAGCGCCGATGCTGTCCTGGCCAAGGCCGTCCTGGCCGCGCGCGAGCAATTGGG
GCTGACGCAGCTCGAACTGGCCGGCATCGTCGGCGTCGATCGCAGCGCCATCAGCCGCTGGAAGACCCAGGGCCTGCGGG
TGGACAGCAAGACCGGCGAGCTGGCTCTGCTGCTGGTGCGAGTCTATCGCGCACTGTATGCCCTGTTCGGCGGGCAGCAG
GAGGACATGCGCCACTTCCTGCGCACTCCCAACCATCACCTGGCGGGCGAGCCGCTGGCACTGATGGGACAGGTGCAGGG
CCTGGTTCATGTGCTGGAATACCTCGATGCGATCCGCGGCAAGGTCTGA
ATGAGCGCTCTCATCAAGGAACGTCCCAGCGCCGATGCTGTCCTGGCCAAGGCCGTCCTGGCCGCGCGCGAGCAATTGGG
GCTGACGCAGCTCGAACTGGCCGGCATCGTCGGCGTCGATCGCAGCGCCATCAGCCGCTGGAAGACCCAGGGCCTGCGGG
TGGACAGCAAGACCGGCGAGCTGGCTCTGCTGCTGGTGCGAGTCTATCGCGCACTGTATGCCCTGTTCGGCGGGCAGCAG
GAGGACATGCGCCACTTCCTGCGCACTCCCAACCATCACCTGGCGGGCGAGCCGCTGGCACTGATGGGACAGGTGCAGGG
CCTGGTTCATGTGCTGGAATACCTCGATGCGATCCGCGGCAAGGTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|