Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/RelE-RelB
Location 2393140..2393729 Replicon chromosome
Accession NZ_CP045422
Organism Devosia sp. S02

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag GDR53_RS11725 Protein ID WP_193334674.1
Coordinates 2393140..2393430 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GDR53_RS11730 Protein ID WP_193334675.1
Coordinates 2393427..2393729 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GDR53_RS11700 2388396..2388962 - 567 WP_193334669.1 elongation factor P -
GDR53_RS11705 2389085..2390218 - 1134 WP_193334670.1 sel1 repeat family protein -
GDR53_RS11710 2390215..2390811 - 597 WP_193334671.1 thiamine phosphate synthase -
GDR53_RS11715 2391005..2392033 - 1029 WP_193334672.1 fructose-bisphosphate aldolase class I -
GDR53_RS11720 2392240..2393070 + 831 WP_193334673.1 aldo/keto reductase -
GDR53_RS11725 2393140..2393430 - 291 WP_193334674.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GDR53_RS11730 2393427..2393729 - 303 WP_193334675.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
GDR53_RS11735 2393799..2395001 - 1203 WP_193334676.1 phosphoglycerate kinase -
GDR53_RS11740 2395088..2395378 - 291 WP_193334677.1 hypothetical protein -
GDR53_RS11745 2395560..2396624 + 1065 WP_193334678.1 MerR family transcriptional regulator -
GDR53_RS11750 2396594..2397133 - 540 WP_193334679.1 putative glycolipid-binding domain-containing protein -
GDR53_RS11755 2397254..2398261 - 1008 WP_193334680.1 type I glyceraldehyde-3-phosphate dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-86)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-59)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10884.39 Da        Isoelectric Point: 9.4722

>T141772 WP_193334674.1 NZ_CP045422:c2393430-2393140 [Devosia sp. S02]
MKLRWTNAARRDREVIYVYVEADNPDAALRLDERFRDRAAQLTGLPYLGRAGRVPGTRELTIAGSSYVLVYRVEPGLVSI
IRVIHTARTWPEDDGA

Download         Length: 291 bp

>T141772 NZ_CP060084:c685403-685101 [Teredinibacter haidensis]
ATGAGCGCATTTACTTTAACACGACGTGCTAAAACTGATTTGAAATCCATAGCTAAATTTACTGAAAAGCGCTGGGGACG
AGAGCAACGCTACATTTACATTAAGCAATTTGATGATACATTTCATGTGCTTTCTAATACCCCCGAAATAGGGAATAACT
GTAACCATATAAAAGAAAATTACCAAAGATTTCCTCAGGGTAGCCATATAATTTTTTATCGCATAGCGACCCAAGGCAGC
ATTCAAATTATTCGTATTCTCCACAAAAACATGGACGTACTCTCAAAATTTGGCGGCTCATAA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11210.65 Da        Isoelectric Point: 4.5854

>AT141772 WP_193334675.1 NZ_CP045422:c2393729-2393427 [Devosia sp. S02]
MAANALIQTRIDPEIKERASEVLALMGLSVSDAVRILLTKVANEGALPFNLTTDPAEYDRWFRAKVQEALDDPRPGYSSE
EVEAYFAEKRAATRRALDRE

Download         Length: 303 bp

>AT141772 NZ_CP060084:c685642-685400 [Teredinibacter haidensis]
ATGGCTAAAAACACAAGTATGACGTTAGGCGAACACTTTGACGGCTTTATTTCTCATCAAATTCAAAGTGGCCGCTATGG
CTCTGCAAGCGAGGTTATACGTGCAGGTTTGAGGGTGCTTGAAGATAAGGAGAGCAAACTTGATGTATTGCGCCAAATGC
TGGCTGACGGAGAAGAAAGCGGTACAGCTGACTATAGCTATGACAGCCTCATGAGTGAACTTGATGCTGAAAGTCATATA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References