Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 5344514..5345753 Replicon chromosome
Accession NZ_CP045380
Organism Labrenzia sp. THAF35

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FIU93_RS24600 Protein ID WP_152507699.1
Coordinates 5345133..5345753 (+) Length 207 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FIU93_RS24595 Protein ID WP_152507040.1
Coordinates 5344514..5345083 (+) Length 190 a.a.

Genomic Context

FIU93_RS24590FIU93_RS24595FIU93_RS24600FIU93_RS24605FIU93_RS24620FIU93_RS24575FIU93_RS24580FIU93_RS24585FIU93_RS24610FIU93_RS24615
Location: 5343799..5344425 (627 bp)
Type: Others
Protein ID: WP_152507039.1
Location: 5344514..5345083 (570 bp)
Type: Antitoxin
Protein ID: WP_152507040.1
Location: 5345133..5345753 (621 bp)
Type: Toxin
Protein ID: WP_152507699.1
Location: 5345893..5346264 (372 bp)
Type: Others
Protein ID: WP_152507041.1
Location: 5348739..5349200 (462 bp)
Type: Others
Protein ID: WP_152507043.1
Location: 5340562..5341410 (849 bp)
Type: Others
Protein ID: WP_023000192.1
Location: 5341593..5342507 (915 bp)
Type: Others
Protein ID: WP_023000193.1
Location: 5342566..5343399 (834 bp)
Type: Others
Protein ID: WP_152507698.1
Location: 5346363..5347151 (789 bp)
Type: Others
Protein ID: WP_023000199.1
Location: 5347168..5348634 (1467 bp)
Type: Others
Protein ID: WP_152507042.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FIU93_RS245755340562..5341410-849WP_023000192.1phosphonate ABC transporter, permease protein PhnE-
FIU93_RS245805341593..5342507-915WP_023000193.1phosphonate ABC transporter substrate-binding protein-
FIU93_RS245855342566..5343399-834WP_152507698.1phosphonate ABC transporter ATP-binding protein-
FIU93_RS245905343799..5344425+627WP_152507039.1chloramphenicol acetyltransferase-
FIU93_RS245955344514..5345083+570WP_152507040.1helix-turn-helix transcriptional regulatorAntitoxin
FIU93_RS246005345133..5345753+621WP_152507699.1HD domain-containing proteinToxin
FIU93_RS246055345893..5346264+372WP_152507041.1STAS/SEC14 domain-containing protein-
FIU93_RS246105346363..5347151-789WP_023000199.1class II glutamine amidotransferase-
FIU93_RS246155347168..5348634-1467WP_152507042.1aminotransferase class V-fold PLP-dependent enzyme-
FIU93_RS246205348739..5349200+462WP_152507043.1Lrp/AsnC family transcriptional regulator-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(28-168)

Antitoxin

Cro/C1-type helix-turn-helix domain

(16-68)


Sequences

Toxin        


Download         Length: 207 a.a.        Molecular weight: 23063.30 Da        Isoelectric Point: 4.7759

>T141758 WP_152507699.1 NZ_CP045380:5345133-5345753 [Labrenzia sp. THAF35]
MTKTPPSLDLPEISHTRLTGLLDFLQAAEQLKDTLRSGTTTGGRPESTAEHSWRLALMVLLFEPELKEVDLLKLLKLTLV
HDLGEAISGDVPAPLQTPGDDRQERERRDFLTLCEPLPGDVAGELTSLWDEYAAARTVEARLAKAFDKLETMLQHVLMPR
QAPSFYEFNLGYGRDRTDCSALTRQLRDEVDKLTRTMMTGAGREIA

Download         Length: 621 bp

>T141758 NZ_CP060083:1957583-1957837 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 190 a.a.        Molecular weight: 21603.56 Da        Isoelectric Point: 7.3881

>AT141758 WP_152507040.1 NZ_CP045380:5344514-5345083 [Labrenzia sp. THAF35]
MQTETAVLESSLGPSLRRWRVLNRVKQEALAHELGVSQTRISRWESGKSQPDDSDRAKITRLLRARPESAADKALLDLVS
RSAVPVHLVCDLTHRLLAISVPRACEWRAPVSEFLNRPLWRFASEGIRATEHRLTDYGWFEPDAPDIVYRTEHVDFPEMT
IPESIIRISRLPLSDGRFARLVREEQDAA

Download         Length: 570 bp

>AT141758 NZ_CP060083:1957335-1957586 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References