Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 2176413..2177569 Replicon chromosome
Accession NZ_CP045367
Organism Marinobacter sp. THAF39

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag FIU96_RS10060 Protein ID WP_152438237.1
Coordinates 2176775..2177569 (+) Length 265 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag FIU96_RS10055 Protein ID WP_152438236.1
Coordinates 2176413..2176778 (+) Length 122 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FIU96_RS10040 2171572..2173176 + 1605 WP_152438233.1 FAD-binding oxidoreductase -
FIU96_RS10045 2173184..2174770 + 1587 WP_152438234.1 glycerol-3-phosphate dehydrogenase/oxidase -
FIU96_RS10050 2174776..2176335 + 1560 WP_152438235.1 FGGY-family carbohydrate kinase -
FIU96_RS10055 2176413..2176778 + 366 WP_152438236.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
FIU96_RS10060 2176775..2177569 + 795 WP_152438237.1 RES family NAD+ phosphorylase Toxin
FIU96_RS10065 2177547..2178953 - 1407 WP_152439637.1 efflux transporter outer membrane subunit -
FIU96_RS10070 2178964..2180904 - 1941 WP_152438238.1 MacB family efflux pump subunit -
FIU96_RS10075 2180901..2182052 - 1152 WP_152438239.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(59-219)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(12-66)


Sequences

Toxin        


Download         Length: 265 a.a.        Molecular weight: 29692.80 Da        Isoelectric Point: 9.8431

>T141752 WP_152438237.1 NZ_CP045367:2176775-2177569 [Marinobacter sp. THAF39]
MNYRERIKGTLGSLQGQLFRVVESQEDIATTRIVDNMQEQARLEQLLDASKPRIPEQASKLHYLLATPFRYPPLKYGSRF
GRSFEPSLFYGAMSIPTALAETAFYRFVFTSHVSEPFKRPLTTLHTVFTARFRSSRGVRLQATEWQDLQKTLTDPVSYRE
SQALGSDLRHCGAEAFQFLSARALQAGLYQLPWQTGSGMDGLNVALFSPRALRDTAPRSYHKLIVATSDQQVSMSLTLAD
GSKQVHNFGREAFLVEGVIPQPAL

Download         Length: 795 bp

>T141752 NZ_CP060083:645309-645623 [Escherichia coli]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA

Antitoxin


Download         Length: 122 a.a.        Molecular weight: 13143.93 Da        Isoelectric Point: 8.5040

>AT141752 WP_152438236.1 NZ_CP045367:2176413-2176778 [Marinobacter sp. THAF39]
MNEPATLAPQTSDKALLAKALLNSAKAFGLSQAEAAAVVGRNRSGLTRDGIDPDSKSGELALLFVRLYRSVYALTGGDNQ
AMAHWLNTPNHYFEGTPRDMIQSTEGLVRVIHYLDAMRGRI

Download         Length: 366 bp

>AT141752 NZ_CP060083:645620-646036 [Escherichia coli]
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACACCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTGCTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTGCCGGAAATTGGCAGTAAATCTATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAATTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References