Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 3819696..3821096 Replicon chromosome
Accession NZ_CP045359
Organism Pseudomonas sp. THAF42

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag FIU98_RS17725 Protein ID WP_152489368.1
Coordinates 3820527..3821096 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag FIU98_RS17720 Protein ID WP_150606047.1
Coordinates 3819696..3820520 (-) Length 275 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FIU98_RS17705 3816580..3817485 - 906 WP_152489367.1 hypothetical protein -
FIU98_RS17710 3817496..3818068 - 573 WP_037049251.1 LemA family protein -
FIU98_RS17715 3818259..3819596 + 1338 WP_037049254.1 peptidase -
FIU98_RS17720 3819696..3820520 - 825 WP_150606047.1 AraC family transcriptional regulator Antitoxin
FIU98_RS17725 3820527..3821096 - 570 WP_152489368.1 GNAT family N-acetyltransferase Toxin
FIU98_RS17730 3821302..3824790 + 3489 WP_152489369.1 hybrid sensor histidine kinase/response regulator -
FIU98_RS17735 3824810..3825622 - 813 WP_037049265.1 MerR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

DNA binding HTH domain, AraC-type

(193-270)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21470.63 Da        Isoelectric Point: 8.0493

>T141748 WP_152489368.1 NZ_CP045359:c3821096-3820527 [Pseudomonas sp. THAF42]
MFKPQLVTLQRGALRLEPLSDADIPALVALAESNRDELLYMSGTQRLDWYRSALADLREQRALPFVVRLGDELVGTTRFA
EFMNTLPACEIGWTWLDRSQHGTGLNGTIKYLMLRHAFDNWGMVRVQLKTAGSNLRSQRAIEKLGAVREGLLRNHRRLAD
GRLDDTVLYSMTDLEWPAVREALEARFGA

Download         Length: 570 bp

>T141748 NZ_CP060076:83732-84043 [Escherichia coli]
ATGCACGTTGTATCGAGAGCACCTTTCGATACAGCCACCAGGCAATTCCCCAATCAGGCAGCGGCACTAGACGACGTATA
CCGGACTTTGAAGAGAGAGAACTACACTTCACCGGACGAAATGAAAAAACGATTTGCCTCGCTGGACAGAATGAAATATC
GGGAGAAGTGGTGGGTGATCGATGTTGGCGGTGGGAATTTAAGGGTGATGTTTTTTGCTGATTTTGAACGTGGGAAAATC
TTTATAAAGCACATAACCACACACGCCGAATACGACAAGCTGACAGATTTTTACCGGAGAACTAAAGAATGA

Antitoxin


Download         Length: 275 a.a.        Molecular weight: 30653.87 Da        Isoelectric Point: 8.2096

>AT141748 WP_150606047.1 NZ_CP045359:c3820520-3819696 [Pseudomonas sp. THAF42]
MESREQTRFWQASALCGVELLQARYLQQRFAPHVHEGFVFTVIEHGAQRFRHRGSDHLAPQGSMVLINPDEVHTGSKAHD
DGWRYRGFYPDNAQVLGALQELGLARSGMPSFAVSVLDDPRLHTAFLQLHRLLEDGAEALQQQLAWREAILLLFQHHGRV
GEAAAPGREPWAVSCAKQMLAEQLLEPPSLEELAAAVNLSPFHFARVFRRATGLPPHAWLKQRRLEQARALLRSGCSAIG
VATQLGFADQSHLSRQFKQVYGVSPGEYRKACLS

Download         Length: 825 bp

>AT141748 NZ_CP060076:84040-84459 [Escherichia coli]
ATGATGTACACCGATGCTATCCAGGCGGCAAACAGCCTGGTTAGCATTGTCCCCCTCCTGGGGGGCAATGCCTCTCGCAA
GGACTATGAAGACGCGCTGACGCTGGTTGAATACCTGGTTGAACACGAGCCAGATCATCCGCTGGTGGACATGCTGGTTG
CGAAAATTGCCCAGTATGAAGATGAGGCGGAAGAGTTCGCAGAGTTCAACGACCGTATTGCAGCGTTACCAAGTGGCGTG
GCCCTGCTGCGTGTCCTGATGGACCAGCACAAACTGACTCAGAGTGATTTTGAGGAAGAGATTGGTAAGAAATCGCTGGT
GAGCCGCATCCTTAACGGGACTCGCTCACTAACACTAGATCACATGAAAGCACTTGCGCGGCGCTTCAACATTCCGCCCA
GCTCATTCATGGACGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References