Detailed information of TA system TA141735

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-Phd
• Location: 1324720..1325267
• Replicon: chromosome
• Accession: NZ_CP045350
• Organism: Vibrio aquimaris strain THAF100

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FIV01_RS06175
• Protein ID: WP_152430216.1
• Coordinates: 1324720..1325022 (-)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: FIV01_RS06180
• Protein ID: WP_152430217.1
• Coordinates: 1325010..1325267 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FIV01_RS06160	1319843..1320928	+	1086	WP_152430213.1	efflux RND transporter periplasmic adaptor subunit	-
FIV01_RS06165	1320921..1324022	+	3102	WP_152430214.1	efflux RND transporter permease subunit	-
FIV01_RS06170	1324088..1324648	+	561	WP_152430215.1	DNA-3-methyladenine glycosylase I	-
FIV01_RS06175	1324720..1325022	-	303	WP_152430216.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FIV01_RS06180	1325010..1325267	-	258	WP_152430217.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
FIV01_RS06190	1325885..1327696	-	1812	WP_152430218.1	hypothetical protein	-
FIV01_RS06195	1327901..1328755	-	855	WP_152430219.1	lipase chaperone	-
FIV01_RS06200	1328767..1329693	-	927	WP_152430220.1	triacylglycerol lipase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-67)

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 11903.94 Da
• Isoelectric Point: 8.0278

>T141735 WP_152430216.1 NZ_CP045350:c1325022-1324720 [Vibrio aquimaris]
MAQVIWTDPALSDLNDIAEYIALENVQMAKRLVQSIFSKIERLEAFPQSGRIIAELKHLNYREVIVNPCRIFYKQEDDKV
FILHVMRSERELRKFLLLRQ

Nucleotide

• Length: 303 bp

>T141735 NZ_CP060075:1161092-1161403 [Escherichia coli]
ATGCACATCATTTCTAAAGCGCCATTTGAAGAGTCTGCGCGTAAATATCCTAACGACGCTCTGGCTCTTCAGGCATTGTA
TCGGGTTATTAAGGAAACGGATTTTTCTACACCAGAAGAAATGCGAACGGCGTTTCCCAACCTCGACAATTTTAGATATC
GCAACAAATGGTACGTTCTGGATGTCGGCGGGAACAATCTTAGGGTTATTGCCTACATAAACTTTGTTAATAAGCGGTTC
TTTGTGAAGCACATAACGAATCACGCAGAGTATGACAAACTGACACGTTACTACAGAGAGAACAAAGAATGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9632.13 Da
• Isoelectric Point: 6.2269

>AT141735 WP_152430217.1 NZ_CP045350:c1325267-1325010 [Vibrio aquimaris]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVEDYEFMQNRLALLEGIARGERALADGDVVSHQEAKDKM
VKWLK

Nucleotide

• Length: 258 bp

>AT141735 NZ_CP060075:1161400-1161819 [Escherichia coli]
ATGACTGCTAATGCTGCACGCGCTGTTAAAGCAACAAGAGAACTGGTCAATGCAGTCCCCTTTCTGGGAGGCAGTGACTC
AGAAGATGATTATCGTGAAGCACTGGAACTGGTCGAATATTTGATTGAAGAAGATGACACCAATCCACTTATCGACTTTC
TGGCGAGCCGCATTGCAGAGTATGAAAACAACAACGAAAAGTTTGCAGAGTTCGACAAAGCCGTTGCGGCAATGCCGGTT
GGCGTGGCGTTACTTCGCACGTTGATTGATCAACATAATCTGACCTATGCGGATTTGAAGAACGAAATCGGCTCTAAATC
CCTGGTCAGTCAGATTTTGTCTGGACAACGATCCCTGACGATATCCCACATTAAGGCACTTTCAGCCCGATTTGGCGTTA
AGCCGGAATGGTTTCTTTGA