Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 27492..28008 Replicon plasmid pTHAF190c_d
Accession NZ_CP045342
Organism Vibrio sp. THAF190c

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag FIV04_RS26265 Protein ID WP_152471360.1
Coordinates 27492..27761 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag FIV04_RS26270 Protein ID WP_152471361.1
Coordinates 27754..28008 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FIV04_RS26240 23270..23698 - 429 WP_152471355.1 TetR/AcrR family transcriptional regulator -
FIV04_RS26245 24226..24558 - 333 WP_152471356.1 hypothetical protein -
FIV04_RS26250 24839..25579 + 741 WP_152471357.1 MipA/OmpV family protein -
FIV04_RS26255 25598..25834 + 237 WP_152471358.1 hypothetical protein -
FIV04_RS26260 26378..27157 - 780 WP_152471359.1 hypothetical protein -
FIV04_RS26265 27492..27761 - 270 WP_152471360.1 Txe/YoeB family addiction module toxin Toxin
FIV04_RS26270 27754..28008 - 255 WP_152471361.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FIV04_RS26275 28153..28419 - 267 WP_152471362.1 hypothetical protein -
FIV04_RS26280 28905..30203 + 1299 WP_152471363.1 hypothetical protein -
FIV04_RS26285 30685..32094 + 1410 WP_152471364.1 GIY-YIG nuclease family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..99578 99578


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(10-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10628.00 Da        Isoelectric Point: 8.8578

>T141725 WP_152471360.1 NZ_CP045342:c27761-27492 [Vibrio sp. THAF190c]
MSSSQRLLSWTDEAWNDYLYWQTQDKKTLKRINKLINDVKRSPFEGIGKPEPLKENLSGFWSRRIDETNRLVYAVDDQAI
TVISCRYHY

Download         Length: 270 bp

>T141725 NZ_CP060073:c3634700-3634302 [Escherichia coli]
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAACTTGATGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGCGATGCACTCTACGACGACTCGTTTACCTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGTGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGAAGCGCATTTGGTATATTGTCAGGGTGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACAGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9617.76 Da        Isoelectric Point: 4.6533

>AT141725 WP_152471361.1 NZ_CP045342:c28008-27754 [Vibrio sp. THAF190c]
MRIVSFTEARNSLKSVLDGVVDDADTTVITRRDSEDAVVMSLDYYNSLMETVHLLRSPKNAEHLSRSIEQYRVGKTTERE
LIDE

Download         Length: 255 bp

>AT141725 NZ_CP060073:c3634996-3634703 [Escherichia coli]
ATGCATCGAATTCTCGCTGAAAAATCGGTCAATATTACTGAGTTACGTAAAAACCCAGCTAAATACTTTATTGATCAACC
GGTTGCGGTTCTTTCTAATAATCGCCCCGCAGGATATCTCTTAAGTGCCAGCGCATTCGAAGCGTTAATGGACATGCTTG
CTGAACAAGAGGAGAAAAAGCCCATAAAGGCGCGCTTCCGTCCAAGTGCTGCAAGATTAGAGGAAATTACACGCCGAGCT
GAAAAATATCTTAATGATATGACGGATGATGATTTCAATGACTTTAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References