Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 358803..359377 Replicon plasmid pTHAF191b_a
Accession NZ_CP045329
Organism Labrenzia sp. THAF191b

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FIV06_RS29485 Protein ID WP_081713154.1
Coordinates 359063..359377 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FIV06_RS29480 Protein ID WP_152512140.1
Coordinates 358803..359033 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FIV06_RS29455 354454..355311 - 858 WP_152512144.1 LysR family transcriptional regulator -
FIV06_RS29460 355410..356561 + 1152 WP_152512143.1 TauD/TfdA family dioxygenase -
FIV06_RS29465 356558..357151 + 594 WP_152512142.1 HD domain-containing protein -
FIV06_RS29470 357148..357993 + 846 WP_152512141.1 alkaline phosphatase family protein -
FIV06_RS29475 358105..358633 - 529 Protein_330 recombinase family protein -
FIV06_RS29480 358803..359033 + 231 WP_152512140.1 ribbon-helix-helix protein, CopG family Antitoxin
FIV06_RS29485 359063..359377 + 315 WP_081713154.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FIV06_RS29495 359926..360522 - 597 WP_051990042.1 XRE family transcriptional regulator -
FIV06_RS29500 360837..362402 + 1566 WP_173014035.1 ABC transporter substrate-binding protein -
FIV06_RS29505 362549..363490 + 942 WP_152512138.1 ABC transporter permease -
FIV06_RS29510 363487..364353 + 867 WP_173014028.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - entE 1..538462 538462
- flank IS/Tn - - 358291..358572 281


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11743.50 Da        Isoelectric Point: 7.9955

>T141718 WP_081713154.1 NZ_CP045329:359063-359377 [Labrenzia sp. THAF191b]
VPRVIVTEGAALGLERCRRFLAVKSSEAGRRAGQAIERQFLLLETPPDFGRPNPDLPELRELLITFGDSGYVSLYRYEPA
VDVLYVLAFRHQKKQATEERVSVV

Download         Length: 315 bp

>T141718 NZ_CP060073:1949792-1949895 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8951.28 Da        Isoelectric Point: 9.8241

>AT141718 WP_152512140.1 NZ_CP045329:358803-359033 [Labrenzia sp. THAF191b]
MATSLKIDDVLKGRVQYLAVKRRRSPHWIMLEAIRQFFEREEACECLKQEALASRSTYQETGRHLTGQEVRTRLNT

Download         Length: 231 bp

>AT141718 NZ_CP060073:c1949933-1949662 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References