Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 5301039..5302278 Replicon chromosome
Accession NZ_CP045328
Organism Labrenzia sp. THAF191b

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FIV06_RS24380 Protein ID WP_152511297.1
Coordinates 5301658..5302278 (+) Length 207 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FIV06_RS24375 Protein ID WP_152511296.1
Coordinates 5301039..5301608 (+) Length 190 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FIV06_RS24355 5297087..5297935 - 849 WP_152511295.1 phosphonate ABC transporter, permease protein PhnE -
FIV06_RS24360 5298118..5299032 - 915 WP_023000193.1 phosphonate ABC transporter substrate-binding protein -
FIV06_RS24365 5299091..5299924 - 834 WP_055659582.1 phosphonate ABC transporter ATP-binding protein -
FIV06_RS24370 5300324..5300950 + 627 WP_055659209.1 chloramphenicol acetyltransferase -
FIV06_RS24375 5301039..5301608 + 570 WP_152511296.1 helix-turn-helix transcriptional regulator Antitoxin
FIV06_RS24380 5301658..5302278 + 621 WP_152511297.1 HD domain-containing protein Toxin
FIV06_RS24385 5302418..5302789 + 372 WP_152511298.1 STAS/SEC14 domain-containing protein -
FIV06_RS24390 5302888..5303676 - 789 WP_023000199.1 class II glutamine amidotransferase -
FIV06_RS24395 5303693..5305165 - 1473 WP_152511299.1 aminotransferase class V-fold PLP-dependent enzyme -
FIV06_RS24400 5305270..5305731 + 462 WP_152511300.1 Lrp/AsnC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(19-158)

Antitoxin

Cro/C1-type helix-turn-helix domain

(16-68)


Sequences

Toxin        


Download         Length: 207 a.a.        Molecular weight: 23133.45 Da        Isoelectric Point: 4.6955

>T141717 WP_152511297.1 NZ_CP045328:5301658-5302278 [Labrenzia sp. THAF191b]
MTKTPPSLDLPEISHTRLTGLLDFLQAAEQLKDTLRSGTTTGGRPESTAEHSWRLALMVLLFEPELKEIDLLKLLKLTLV
HDLGEAISGDVPAPLQTLGDDRQERERRDFLTLCKPLPGDVAGELLSLWDEYAAARTAEARLAKAFDKLETMLQHVLMPR
QAPPFYEFNLGYGRDRTDCSALTRQLRDEVDEMTRAMMTDAGREIA

Download         Length: 621 bp

>T141717 NZ_CP060073:1015384-1015719 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin


Download         Length: 190 a.a.        Molecular weight: 21620.57 Da        Isoelectric Point: 7.3889

>AT141717 WP_152511296.1 NZ_CP045328:5301039-5301608 [Labrenzia sp. THAF191b]
MQTETAVLETSLGPSLRRWRVLNRVKQEALAHELGVSQTRISRWESGKSQPDDSDRAKITRLLRARPESAADKALLDLVS
RSAVPVHLVCDLTHRLLAMSVPRACEWRAPVNDFLNRPLWRFASEGIRATEHRLTDFGWFEPDAPDIVYRTEHVDFPEMT
IPESTIRISRLPLSDGRFARLVREEQDAA

Download         Length: 570 bp

>AT141717 NZ_CP060073:1015136-1015384 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References