Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 894685..895201 Replicon chromosome
Accession NZ_CP045302
Organism Azotobacter salinestris strain KACC 13899

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GCU53_RS04230 Protein ID WP_152386504.1
Coordinates 894920..895201 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GCU53_RS04225 Protein ID WP_152386503.1
Coordinates 894685..894930 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GCU53_RS04200 889694..890674 + 981 WP_152385958.1 IS5 family transposase -
GCU53_RS04210 891237..892754 + 1518 WP_152386501.1 transposase -
GCU53_RS04215 893106..894149 + 1044 WP_152386502.1 hypothetical protein -
GCU53_RS04220 894289..894444 + 156 Protein_774 nuclease -
GCU53_RS04225 894685..894930 + 246 WP_152386503.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GCU53_RS04230 894920..895201 + 282 WP_152386504.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GCU53_RS04235 895359..895634 + 276 WP_152386505.1 BrnT family toxin -
GCU53_RS04240 895612..895917 + 306 WP_152386506.1 BrnA antitoxin family protein -
GCU53_RS04245 896083..896475 - 393 WP_152386507.1 hypothetical protein -
GCU53_RS04250 896476..899757 - 3282 WP_152386508.1 tape measure protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 860544..925585 65041


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-71)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10943.82 Da        Isoelectric Point: 10.4971

>T141671 WP_152386504.1 NZ_CP045302:894920-895201 [Azotobacter salinestris]
MTYSLEFLPSALKEWEKLGHTVREQLKKKLRERLELPRVPPDALREMPNHYKIKLRASGYRLVYRVEDERVVVVVVAVGK
REHSAAYEKAKGR

Download         Length: 282 bp

>T141671 NZ_CP060061:928477-928884 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCTGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8615.86 Da        Isoelectric Point: 4.4963

>AT141671 WP_152386503.1 NZ_CP045302:894685-894930 [Azotobacter salinestris]
MQNVLANKAVSVSELKKNPSAVIGSANGGPVAVLNHNRVMGYMVPAAEFEAMVERLEDLELAELARSRAGETPVPVNLDD
L

Download         Length: 246 bp

>AT141671 NZ_CP060061:928230-928496 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References