Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3938812..3939475 Replicon chromosome
Accession NZ_CP045300
Organism Kosakonia arachidis strain KACC 18508

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag GCU50_RS19520 Protein ID WP_090121197.1
Coordinates 3939059..3939475 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag GCU50_RS19515 Protein ID WP_090121199.1
Coordinates 3938812..3939078 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GCU50_RS19495 3934261..3935694 - 1434 WP_090121204.1 6-phospho-beta-glucosidase -
GCU50_RS19500 3935811..3936539 - 729 WP_090121203.1 MurR/RpiR family transcriptional regulator -
GCU50_RS19505 3936885..3937544 + 660 WP_090121202.1 hemolysin III family protein -
GCU50_RS19510 3937584..3938564 - 981 WP_090121200.1 tRNA-modifying protein YgfZ -
GCU50_RS19515 3938812..3939078 + 267 WP_090121199.1 FAD assembly factor SdhE Antitoxin
GCU50_RS19520 3939059..3939475 + 417 WP_090121197.1 protein YgfX Toxin
GCU50_RS19525 3939495..3940016 - 522 WP_090121196.1 flavodoxin FldB -
GCU50_RS19530 3940117..3941013 + 897 WP_090121194.1 site-specific tyrosine recombinase XerD -
GCU50_RS19535 3941038..3941751 + 714 WP_090121193.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
GCU50_RS19540 3941757..3943490 + 1734 WP_090121191.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16269.18 Da        Isoelectric Point: 10.2053

>T141667 WP_090121197.1 NZ_CP045300:3939059-3939475 [Kosakonia arachidis]
VVLWQSELRVSWRAQWISLLLHGLGAALILLMPWPLSYTPLWLLLLSLVVFDCVRSQRRINACHGELKLLMDSRLRWQGV
EWDIIGAPWMLRSGMMLRLRREEDGRHQHLWLAADSMDAQEWRDLRRVISQKPAQGLH

Download         Length: 417 bp

>T141667 NZ_CP060061:c603520-603056 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAAACAGAAGAAACCCATTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10483.95 Da        Isoelectric Point: 5.6062

>AT141667 WP_090121199.1 NZ_CP045300:3938812-3939078 [Kosakonia arachidis]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDTLSDADKQLFVRLLESDDPDLFNWLMNHGKPQDAELQRMVQLIQTRN
RDRGPVAI

Download         Length: 267 bp

>AT141667 NZ_CP060061:c603855-603520 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References