141663

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 1621973..1622495 Replicon chromosome
Accession NZ_CP045300
Organism Kosakonia arachidis strain KACC 18508

Toxin (Protein)


Gene name stbE Uniprot ID -
Locus tag GCU50_RS08180 Protein ID WP_090118818.1
Coordinates 1622211..1622495 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID -
Locus tag GCU50_RS08175 Protein ID WP_090118820.1
Coordinates 1621973..1622221 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GCU50_RS08135 1617464..1618384 - 921 WP_090118835.1 hypothetical protein -
GCU50_RS08140 1618802..1618981 - 180 WP_090118833.1 hypothetical protein -
GCU50_RS08145 1619090..1619269 - 180 WP_090118831.1 hypothetical protein -
GCU50_RS08150 1619509..1619826 + 318 WP_090118829.1 hypothetical protein -
GCU50_RS08155 1620032..1620301 + 270 WP_090118827.1 DUF1778 domain-containing protein -
GCU50_RS08160 1620305..1620826 + 522 WP_090118825.1 GNAT family N-acetyltransferase -
GCU50_RS08165 1620860..1621087 - 228 WP_090118824.1 helix-turn-helix domain-containing protein -
GCU50_RS08170 1621195..1621449 + 255 WP_090118822.1 helix-turn-helix domain-containing protein -
GCU50_RS08175 1621973..1622221 + 249 WP_090118820.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
GCU50_RS08180 1622211..1622495 + 285 WP_090118818.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GCU50_RS08185 1622669..1623241 + 573 WP_090118817.1 DUF1349 domain-containing protein -
GCU50_RS08190 1623422..1624003 - 582 WP_167518523.1 TetR/AcrR family transcriptional regulator -
GCU50_RS08195 1624128..1624709 + 582 WP_090118812.1 hypothetical protein -
GCU50_RS08200 1625449..1626795 - 1347 WP_090118810.1 PTS cellobiose transporter subunit IIC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11039.71 Da        Isoelectric Point: 10.6993

>T141663 WP_090118818.1 NZ_CP045300:1622211-1622495 [Kosakonia arachidis]
MTYKLAFNESALKEWKKLGHTVREQFKKKLTERLQNPRVPASQLYGRKDQFKIKLRGAGYRLVYSVNDDIVTVTVIGVGK
RENDDIYNVTRHRN

Download         Length: 285 bp

>T141663 NZ_CP060057:c4790850-4790677 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8940.18 Da        Isoelectric Point: 3.8209

>AT141663 WP_090118820.1 NZ_CP045300:1621973-1622221 [Kosakonia arachidis]
MAFQILTTTAASITELKRDPMGTFNAGEGAAVAILNRNEPAFYCVPPALYAQLMEILEDQELGRIADERIGEAVIEVNID
DL

Download         Length: 249 bp

>AT141663 NZ_CP060057:c4791174-4790878 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGATT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAACT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTCAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References