141662

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) KacT-ataR/DUF1778(antitoxin)
Location 1620032..1620826 Replicon chromosome
Accession NZ_CP045300
Organism Kosakonia arachidis strain KACC 18508

Toxin (Protein)


Gene name KacT Uniprot ID -
Locus tag GCU50_RS08160 Protein ID WP_090118825.1
Coordinates 1620305..1620826 (+) Length 174 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag GCU50_RS08155 Protein ID WP_090118827.1
Coordinates 1620032..1620301 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GCU50_RS08120 1615454..1616068 + 615 WP_090118840.1 methylthioribulose 1-phosphate dehydratase -
GCU50_RS08125 1616065..1616754 + 690 WP_090118838.1 acireductone synthase -
GCU50_RS08130 1616751..1617293 + 543 WP_090118836.1 acireductone dioxygenase -
GCU50_RS08135 1617464..1618384 - 921 WP_090118835.1 hypothetical protein -
GCU50_RS08140 1618802..1618981 - 180 WP_090118833.1 hypothetical protein -
GCU50_RS08145 1619090..1619269 - 180 WP_090118831.1 hypothetical protein -
GCU50_RS08150 1619509..1619826 + 318 WP_090118829.1 hypothetical protein -
GCU50_RS08155 1620032..1620301 + 270 WP_090118827.1 DUF1778 domain-containing protein Antitoxin
GCU50_RS08160 1620305..1620826 + 522 WP_090118825.1 GNAT family N-acetyltransferase Toxin
GCU50_RS08165 1620860..1621087 - 228 WP_090118824.1 helix-turn-helix domain-containing protein -
GCU50_RS08170 1621195..1621449 + 255 WP_090118822.1 helix-turn-helix domain-containing protein -
GCU50_RS08175 1621973..1622221 + 249 WP_090118820.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
GCU50_RS08180 1622211..1622495 + 285 WP_090118818.1 type II toxin-antitoxin system RelE/ParE family toxin -
GCU50_RS08185 1622669..1623241 + 573 WP_090118817.1 DUF1349 domain-containing protein -
GCU50_RS08190 1623422..1624003 - 582 WP_167518523.1 TetR/AcrR family transcriptional regulator -
GCU50_RS08195 1624128..1624709 + 582 WP_090118812.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(90-150)

Antitoxin

Vibrio phage ICP1, Orf50

(8-86)


Sequences

Toxin        


Download         Length: 174 a.a.        Molecular weight: 19346.37 Da        Isoelectric Point: 9.0381

>T141662 WP_090118825.1 NZ_CP045300:1620305-1620826 [Kosakonia arachidis]
VDNLTIEMFSGETAYETGGFDCGEVSLNAFLTHHLKRQHDGKILRAWLLVTKTPRPRILGYYTLSGGSFEKERLPTKTQQ
KKVPYCNVPCVISGRLAIDKSLQGNGWGEILVAHAMKVVFNTSLTIGIHGLFVEALTGKAKKFYEKLGFIPLTDGNPHSL
FYPTKSIERLFEE

Download         Length: 522 bp

>T141662 NZ_CP060057:4453424-4453681 [Escherichia coli]
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10272.79 Da        Isoelectric Point: 8.7348

>AT141662 WP_090118827.1 NZ_CP045300:1620032-1620301 [Kosakonia arachidis]
MPALKKQRIDLRLTDEDKKMIEEAAAMTNQTVTQFLVNSASERAAEVIEQHRRLILSEESWNRVMDAIENPPAPNNKLKR
AAKRLQNME

Download         Length: 270 bp

>AT141662 NZ_CP060057:4453693-4454238 [Escherichia coli]
ATGACAGTACACCACTTCACTTTTCATATCACAGATAAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTTAGCAAAGAAGCCGATTTAGTGACCTCTTTACTTGAGGATGAAAGCGCGCGCCCCGCGTTATCGCTGCTAGCCC
GGTATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCAACCTTCAAAGGAGAAATGGATTCACCGTTGATGCAC
ATCCTCGCTCCCCTGGCGGTCATACCGGAATACCAAGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAATCACTCACCGCT
CAGCCCATGACCCTGACCGGCCACATCCGGTGCGCAGACCCTGATGAAACCGGAGCACTGACGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References