Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2067662..2067807 Replicon chromosome
Accession NZ_CP045263
Organism Klebsiella pneumoniae strain 16HN-263

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2067698..2067800 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2067662..2067807 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELO34_RS10380 2062792..2064852 + 2061 WP_004151449.1 oligopeptidase B -
ELO34_RS10385 2064856..2065515 - 660 WP_002911407.1 exodeoxyribonuclease X -
ELO34_RS10390 2065594..2065824 - 231 WP_002911406.1 DNA polymerase III subunit theta -
ELO34_RS10395 2065937..2066311 + 375 WP_004151448.1 CopC domain-containing protein YobA -
ELO34_RS10400 2066315..2067184 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
ELO34_RS10405 2067201..2067539 + 339 WP_002911404.1 YebY family protein -
- 2067662..2067807 - 146 - - Antitoxin
- 2067698..2067800 + 103 - - Toxin
ELO34_RS10410 2068175..2068318 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
ELO34_RS10415 2068423..2069391 - 969 WP_004151446.1 VirK/YbjX family protein -
ELO34_RS10420 2069548..2070201 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
ELO34_RS10425 2070198..2070389 - 192 WP_002911395.1 YebW family protein -
ELO34_RS10430 2070487..2070726 - 240 WP_002911393.1 YebV family protein -
ELO34_RS10435 2070842..2072275 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T141584 NZ_CP045263:2067698-2067800 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT141584 NZ_CP045263:c2067807-2067662 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References