Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-PHD
Location 206523..207191 Replicon chromosome
Accession NZ_CP045245
Organism Cellulomonas sp. JZ18

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GC089_RS00950 Protein ID WP_155376105.1
Coordinates 206523..206915 (-) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GC089_RS00955 Protein ID WP_155376106.1
Coordinates 206919..207191 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GC089_RS00935 202765..203322 - 558 WP_155376103.1 hypothetical protein -
GC089_RS00940 203388..204353 - 966 WP_155376104.1 HNH endonuclease -
GC089_RS00945 204408..206279 - 1872 WP_155378848.1 DUF2075 domain-containing protein -
GC089_RS00950 206523..206915 - 393 WP_155376105.1 type II toxin-antitoxin system VapC family toxin Toxin
GC089_RS00955 206919..207191 - 273 WP_155376106.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GC089_RS00960 207427..208146 + 720 WP_155376107.1 DUF4241 domain-containing protein -
GC089_RS00965 208785..209090 + 306 WP_155378849.1 excalibur calcium-binding domain-containing protein -
GC089_RS00970 209103..210181 - 1079 Protein_189 PKD domain-containing protein -
GC089_RS00975 210693..211334 - 642 WP_155376108.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-120)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-41)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14151.19 Da        Isoelectric Point: 4.6327

>T141547 WP_155376105.1 NZ_CP045245:c206915-206523 [Cellulomonas sp. JZ18]
VAHYLDTSALVKLVVEEPETDALRTWWRQHGTTPVACDLVRTELMRAVRRATPEAAVQAHAVLDALVLLQATPRVFDVAG
RLEPATLRSLDAIHLAAALELGDELEGMVTYDERLAEAAEAYGVAVLAPR

Download         Length: 393 bp

>T141547 NZ_CP060009:c317088-316801 [Pseudomonas sediminis]
ATGATCTATAGCCTCGAATTCGATGCACGAGCACTGAAGGAGTGGCACAAGCTGGGGGACACCGTCCGCGAACAGCTCAA
GAAAAAGCTCGCGGAGGTGCTGGTCAATCCGCGGGTCGAGGCGAATCGCCTTCACTCGCTACCCGACTGCTACAAAATCA
AGCTGCGCAGCAGTGGTTATCGCTTGGTCTATCAGGTGATCGACCATGAAGTGGTGGTATTTGTCGTCGCGGTGGATCGA
CGTGACCGTGAGCAGGCTTACCGCAAGGCCGCTGAGCGGCTTAAATAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9309.60 Da        Isoelectric Point: 11.2212

>AT141547 WP_155376106.1 NZ_CP045245:c207191-206919 [Cellulomonas sp. JZ18]
MASVGIRELKQNASAVVARVAAGETVTVTDRGRPAAQLTPIPASPLARLVKSGAARPARGDLAELPAPRPARAGQPSLSD
TLADMRDDER

Download         Length: 273 bp

>AT141547 NZ_CP060009:c317317-317078 [Pseudomonas sediminis]
ATGGCGTCCATCAATATCCGCATCGACGACGAGCTTAAAGTCCGGGCTTACCGGGAACTGGAAAAGCTCGGCGTCACCCC
TTCTGAGCTGATGCGCCAAGCCCTGCAATACGTGGCCGAGCGCGGGCAGCTGCCTTTCCGTCCGGTACTGATGACCGAGG
AAGATGAAGCCCTGATTGCCACGGTGCGTGAGCGCATTGCTGCTCCGCAGCGCGTGAAGGTCTCGCTGGATGATCTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References