Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazE-MazF
Location 5117506..5118083 Replicon chromosome
Accession NZ_CP045226
Organism Nostoc sphaeroides CCNUC1

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag GXM_RS23090 Protein ID WP_118166977.1
Coordinates 5117506..5117766 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag GXM_RS23095 Protein ID WP_118166976.1
Coordinates 5117754..5118083 (+) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GXM_RS23075 5113757..5114980 + 1224 WP_152590082.1 type II secretion system F family protein -
GXM_RS23080 5115163..5115723 + 561 WP_118166979.1 hypothetical protein -
GXM_RS23085 5115959..5116981 - 1023 WP_152590083.1 saccharopine dehydrogenase-like oxidoreductase -
GXM_RS23090 5117506..5117766 + 261 WP_118166977.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Toxin
GXM_RS23095 5117754..5118083 + 330 WP_118166976.1 type II toxin-antitoxin system PemK/MazF family toxin Antitoxin
GXM_RS23100 5118314..5118538 + 225 WP_118166975.1 DUF433 domain-containing protein -
GXM_RS23105 5118522..5118848 + 327 WP_118166974.1 DUF5615 family PIN-like protein -
GXM_RS23110 5119428..5119637 + 210 WP_012406943.1 DUF2997 domain-containing protein -
GXM_RS23115 5119677..5120063 + 387 WP_118166973.1 DUF1257 domain-containing protein -
GXM_RS23120 5120063..5120524 + 462 WP_152590084.1 ferredoxin -
GXM_RS23125 5120876..5121160 - 285 WP_094328132.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

SpoVT-AbrB domain

(10-50)

Antitoxin

mRNA interferase PemK-like

(7-107)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9857.13 Da        Isoelectric Point: 4.6856

>T141534 WP_118166977.1 NZ_CP045226:5117506-5117766 [Nostoc sphaeroides CCNUC1]
MGTAIRTRIVKIGNSQGIRIPKLLLEQSGIGEEVEIEIQDCHLIIRAASQSRKGWEEAFATMAKQHDDALLDDAVTTEWE
HREWEW

Download         Length: 261 bp

>T141534 NZ_CP060001:c79611-79210 [Xanthomonas citri pv. citri]
ATGAAGCGGTACATGCTTGATACCAACACCGTGAGCCATCTCGTCAAGAGCCATCCGGCTGTCTCTCGACGGGTCATTGA
AGTGCCTATGACTGCGCTATGTATGTCCGCAATTACCGGTGGGGAGCTGATGTTCGGCTTGGCTAAGGTGCCAGACGCCA
AACGCCTTCAGCAAGCCGTCATGGAACTCCTGCGGCGCGTGGATGTGCTGCCTTGGGATGGCGCGGTAATGGAGCGTTAC
GGAAGCGTAAGAGCGGACCTAGAAAAGCAAGGTAAAGCGCTTGGGTCGCTCGACATGCTTATCGCAGCACATGCACTGGA
AACGGATTCTGTCCTCGTTACCAATGACGCCGCATTTAGTCGTGTTGTTGGTTTGACCGTGGAAGATTGGACACGCAGCT
AA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12118.99 Da        Isoelectric Point: 4.7729

>AT141534 WP_118166976.1 NZ_CP045226:5117754-5118083 [Nostoc sphaeroides CCNUC1]
VGVVVNRFDVFLVNLDPTMGSEIQKTRPCVVISPDEMNKYITTVIVAPMTTKGQSYPTRVACQFQGNDGQIVLDQIRTVD
KTRLVKKLGQIDSDEQKAVLDTLAEMFAE

Download         Length: 330 bp

>AT141534 NZ_CP060001:c79868-79608 [Xanthomonas citri pv. citri]
GTGAGCCAAGTTGCCAAGCTGTTCATCAATGGCCGCAGCCAGGCAGTCCGCTTGCCTGCCGCCTATCGCTTTACCGAGAA
AGAGGTTTTCATTCGCCAAGACCCGGAGACCGGTGACGTCATCCTGTCTCGGAAGCCTGCAACGTGGGAGGACTTCTTTA
TCGTACTCAAGAGCGCAGATGTGCCTGCTAATTTTCTAGATGCCGCCGAGCGCAATCAGGGCACGCAGGACCGTGATCCT
TTTGCGGGATGGCGCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References