Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 3071288..3071894 Replicon chromosome
Accession NZ_CP045226
Organism Nostoc sphaeroides CCNUC1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GXM_RS13865 Protein ID WP_152589230.1
Coordinates 3071529..3071894 (+) Length 122 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GXM_RS13860 Protein ID WP_118168548.1
Coordinates 3071288..3071539 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GXM_RS13840 3067251..3068147 + 897 WP_118168556.1 MBL fold metallo-hydrolase -
GXM_RS13845 3068510..3069574 + 1065 WP_118168554.1 bifunctional riboflavin kinase/FAD synthetase -
GXM_RS13850 3069738..3070646 + 909 WP_118168552.1 MoxR family ATPase -
GXM_RS13855 3070799..3071164 + 366 WP_118168550.1 hypothetical protein -
GXM_RS13860 3071288..3071539 + 252 WP_118168548.1 hypothetical protein Antitoxin
GXM_RS13865 3071529..3071894 + 366 WP_152589230.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GXM_RS13870 3072044..3072640 + 597 WP_194198787.1 cytochrome C -
GXM_RS13875 3072991..3075783 + 2793 WP_118168540.1 preprotein translocase subunit SecA -
GXM_RS13880 3075889..3076347 + 459 WP_118168538.1 aspartyl protease family protein -
GXM_RS13885 3076376..3076846 + 471 WP_118168536.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-108)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13881.72 Da        Isoelectric Point: 8.3099

>T141532 WP_152589230.1 NZ_CP045226:3071529-3071894 [Nostoc sphaeroides CCNUC1]
MPNEQPSVLIDLTPEYKQNLRYLSKRFRNIRSDVQPIIEQLQQGNIVGDRISSIGEEYIVYKVRVRNSSIQKGKSAGYRL
IYQVESPTSILLLTIYSKSDREDIGANEIRDILADFSSKSD

Download         Length: 366 bp

>T141532 NZ_CP060001:40055-40387 [Xanthomonas citri pv. citri]
ATGGATCGCGGCGATGTCTATTTGGTTTCGCTCGATCCCACGTCCGGCCATGAACAACAGGGCACGCGCCCGGTGCTGAT
TGTGTCGCCAAGCGCGTTCAACCGCCTGACGAAAACACCGGTCGTGCTGCCGATCACCAGTGGGGGTAACTTCGCCCGCA
CGGCAGGCTTTACCGTGTCGCTCATGGGTGCGGGTACCAACACAACTGGCGTAGTTCGCTGCGATCAGCCCCGCGCTCTC
GATCTAGCCTCGCGGCGCGCGCGCAAGCTGGAAACCGTGCCGTCCCCGATCATGGATGAGGTATTAGCGAAGCTGAGCGC
GATCCTTGAGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9238.45 Da        Isoelectric Point: 4.1593

>AT141532 WP_118168548.1 NZ_CP045226:3071288-3071539 [Nostoc sphaeroides CCNUC1]
MKAIEVTGKIDSQGNLVLDEPIQGTTYPHQVRVIVLVPEQLEEVDPDDTTVEEIKASLRRALQQAKAGQRLPLSEMWEGI
DAE

Download         Length: 252 bp

>AT141532 NZ_CP060001:39798-40055 [Xanthomonas citri pv. citri]
ATGCATACGACCAATCTGCGTAAGGTCGGTGGCTCGATCATGTTGGCTGTCCCGCCCGCCATTCTGGATATGCTGCGTCT
GCGTGCCGGCGCTACCGTTGGCTTGGCCGTCGATCATGGTCGCCTGGTGATCGAACCCACGCTGCGTCCGTACTACAGCC
TGGATGAGCTGCTGGCCCAATGCGACGCATCCGCCGAACTCTCCACCGAAGATCGGGAATGGCTCGACGCCAAGCCTGTT
GGCAGCGAGCTGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References