Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-PHD
Location 807910..808550 Replicon chromosome
Accession NZ_CP045226
Organism Nostoc sphaeroides CCNUC1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GXM_RS03645 Protein ID WP_118163665.1
Coordinates 807910..808308 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GXM_RS03650 Protein ID WP_118163661.1
Coordinates 808305..808550 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GXM_RS03610 804169..804543 + 375 WP_118163691.1 hypothetical protein -
GXM_RS03615 804590..805060 - 471 WP_118163687.1 hydrogenase maturation protease -
GXM_RS03620 805148..805423 + 276 WP_118163684.1 DUF2281 domain-containing protein -
GXM_RS03625 805420..805833 + 414 WP_152588238.1 PIN domain-containing protein -
GXM_RS03630 805902..806324 - 423 WP_152588239.1 hypothetical protein -
GXM_RS03635 806637..806969 - 333 WP_152588240.1 winged helix-turn-helix transcriptional regulator -
GXM_RS03640 807072..807809 + 738 WP_152588241.1 SDR family oxidoreductase -
GXM_RS03645 807910..808308 - 399 WP_118163665.1 type II toxin-antitoxin system VapC family toxin Toxin
GXM_RS03650 808305..808550 - 246 WP_118163661.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
GXM_RS03655 808691..808901 + 211 Protein_715 type II toxin-antitoxin system HicB family antitoxin -
GXM_RS03660 808962..809378 - 417 WP_152588242.1 HNH endonuclease -
GXM_RS03665 809375..809584 - 210 WP_118163653.1 hypothetical protein -
GXM_RS03670 809672..810772 - 1101 Protein_718 nickel-dependent hydrogenase large subunit -
GXM_RS03675 810889..812349 + 1461 WP_152588243.1 site-specific integrase -
GXM_RS03680 812650..813453 + 804 WP_152590677.1 cold shock domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-41)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14969.39 Da        Isoelectric Point: 4.6485

>T141529 WP_118163665.1 NZ_CP045226:c808308-807910 [Nostoc sphaeroides CCNUC1]
VKLLLDTQCWLWWFTQPELLNEAAIAHIADETNELWLSVASIWEIGIKVAIGKLPLPDPLDSYISSRMTVLAMRSLEITA
SHALQAAALPLHHRDPFDRMFIAQAQIEEMTLVSADSMFYKYDISLLWAAKS

Download         Length: 399 bp

>T141529 NZ_CP060000:60068-60400 [Xanthomonas citri pv. citri]
ATGGATCGCGGCGATGTCTATTTGGTTTCGCTCGATCCCACGTCCGGCCATGAACAACAGGGCACGCGCCCGGTGCTGAT
TGTGTCGCCAAGCGCGTTCAACCGCCTGACGAAAACACCGGTCGTGCTGCCGATCACCAGTGGGGGTAACTTCGCCCGCA
CGGCAGGCTTTACCGTGTCGCTCATGGGTGCGGGTACCAACACAACTGGCGTAGTTCGCTGCGATCAGCCCCGCGCTCTC
GATCTAGCCTCGCGGCGCGCGCGCAAGCTGGAAACCGTGCCGTCCCCGATCATGGATGAGGTATTAGCGAAGCTGAGCGC
GATCCTTGAGTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8912.09 Da        Isoelectric Point: 4.7616

>AT141529 WP_118163661.1 NZ_CP045226:c808550-808305 [Nostoc sphaeroides CCNUC1]
METVNIHQAKTNLSKLLSRVELGEEIIISNRGIPVAKLVPFHNSSNRLNSLGQDKGRFVVPDDFNAPLPEEILAAFEGGE
E

Download         Length: 246 bp

>AT141529 NZ_CP060000:59811-60068 [Xanthomonas citri pv. citri]
ATGCATACGACCAATCTGCGTAAGGTCGGTGGCTCGATCATGTTGGCTGTCCCGCCCGCCATTCTGGATATGCTGCGTCT
GCGTGCCGGCGCTACCGTTGGCTTGGCCGTCGATCATGGTCGCCTGGTGATCGAACCCACGCTGCGTCCGTACTACAGCC
TGGATGAGCTGCTGGCCCAATGCGACGCATCCGCCGAACTCTCCACCGAAGATCGGGAATGGCTCGACGCCAAGCCTGTT
GGCAGCGAGCTGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References