Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3918923..3919827 Replicon chromosome
Accession NZ_CP045216
Organism Pantoea dispersa strain BJQ0007

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag GAY20_RS18585 Protein ID WP_152391420.1
Coordinates 3919363..3919827 (+) Length 155 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A246NMT1
Locus tag GAY20_RS18580 Protein ID WP_058757556.1
Coordinates 3918923..3919366 (+) Length 148 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GAY20_RS18560 3915034..3915429 + 396 WP_031279757.1 transposase -
GAY20_RS18565 3916339..3917292 - 954 WP_152391419.1 DMT family transporter -
GAY20_RS18570 3917365..3918195 - 831 WP_058757554.1 AraC family transcriptional regulator -
GAY20_RS18575 3918322..3918849 + 528 WP_059009915.1 isochorismatase family protein -
GAY20_RS18580 3918923..3919366 + 444 WP_058757556.1 DUF2384 domain-containing protein Antitoxin
GAY20_RS18585 3919363..3919827 + 465 WP_152391420.1 RES domain-containing protein Toxin
GAY20_RS18590 3920357..3920911 + 555 WP_152391421.1 hypothetical protein -
GAY20_RS18595 3920973..3921515 - 543 WP_021507842.1 single-stranded DNA-binding protein SSB1 -
GAY20_RS18600 3921737..3924565 + 2829 WP_021507843.1 excinuclease ABC subunit UvrA -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-148)

Antitoxin

(15-147)


Sequences


Toxin        


Download         Length: 155 a.a.        Molecular weight: 17137.65 Da        Isoelectric Point: 6.3296

>T141517 WP_152391420.1 NZ_CP045216:3919363-3919827 [Pantoea dispersa]
VIFYRLTKSQYAAEAWSGYGAKQYGGRWNHKGYPTVYVATSVSLAALEVLVHIGRESVLDEYTLFSIDIPDAEVAYLAEA
FLPPDWRHDPAPLSTMDLGTGWLQSAEGAALMLPSTIIPMENKAILNPLHHSFKSALTRVKELPFVFDQRLIKG

Download         Length: 465 bp

>T141517 NZ_CP059996:8811-9107 [Sulfurospirillum sp. ACSDCE]
ATGTATACTCCTGAGTATCATCGTTTCTTTAAAAAAGATATAGAACGTGATAAAAAAAGTGGTCAGTTTTCAGCAGAGGA
TTTCACACTTTTAAAAGAGGTAATGTCCGCGATGTTGAATGATGAGATTCTTCATGAAAAGTATAAAAACCACCCCTTAA
AAGGGGAATGGGAAGGAACTTATGAATGTCACATTAAAAATGATTGGCTTTTAATTTATCAGATAGATAACAATACAAAT
GAAATGATATTTATGAGACTTGGTGCACACGCTCAAATATTTAAAAAATATAAATAA

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16114.59 Da        Isoelectric Point: 9.9132

>AT141517 WP_058757556.1 NZ_CP045216:3918923-3919366 [Pantoea dispersa]
MRAYIPQPGANDNALWRVAGLPPRGIELTRMLEAGLPVAVIDDIRHWSAMTRAEIMKVTGINERNIARRKSTGKSLSPDE
SERVARFVRVMDAAVQLFAGNKEEATQWLSRPVKGLGNVAPITLLTTESGALDVLDLIGRLEHGVFS

Download         Length: 444 bp

>AT141517 NZ_CP059996:8554-8811 [Sulfurospirillum sp. ACSDCE]
ATGACCGGAACAGCTATGACAGTACGCATTGATCCTGATATCAAAAATAAAGCAGCAGAATATCTCAAGCAAATGGGATT
AACTACCAGCGAAGCTACACGACTTTTTTTACATAGTGTTGTACTTCACAAAGGTCTTCCTTTTGAGCTTCGCATTCCTA
ATGAAAAAACAGTGACAGCAATCAAAGAAACAAAAGAGGGCAAGAATATTATTAAACATACTTCCCCTAAAGAATTGTTT
GATGATTTAGGATTGTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A246NMT1

References