Detailed information of TA system TA141512

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1898812..1899347
• Replicon: chromosome
• Accession: NZ_CP045216
• Organism: Pantoea dispersa strain BJQ0007

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A246NE43
• Locus tag: GAY20_RS08850
• Protein ID: WP_058770149.1
• Coordinates: 1898812..1899099 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: GAY20_RS08855
• Protein ID: WP_058770150.1
• Coordinates: 1899096..1899347 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GAY20_RS08830	1894558..1895529	+	972	WP_152390829.1	autoinducer 2 ABC transporter substrate-binding protein	-
GAY20_RS08835	1895541..1896482	+	942	WP_152390830.1	ABC transporter permease	-
GAY20_RS08840	1896479..1897423	+	945	WP_021509450.1	ABC transporter permease	-
GAY20_RS08845	1897427..1898761	+	1335	WP_152390831.1	ArgE/DapE family deacylase	-
GAY20_RS08850	1898812..1899099	-	288	WP_058770149.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
GAY20_RS08855	1899096..1899347	-	252	WP_058770150.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
GAY20_RS08860	1899479..1901668	-	2190	WP_152390832.1	xanthine dehydrogenase family protein molybdopterin-binding subunit	-
GAY20_RS08865	1901665..1902621	-	957	WP_152390833.1	xanthine dehydrogenase family protein subunit M	-
GAY20_RS08870	1902618..1903238	-	621	WP_152390834.1	aldehyde dehydrogenase iron-sulfur subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11155.16 Da
• Isoelectric Point: 10.4346

>T141512 WP_058770149.1 NZ_CP045216:c1899099-1898812 [Pantoea dispersa]
VTWTVKFREEALKEWHKLDKAIQQQFAKKLKKCCENPHIPSAKLRGIKDCYKIKLRASGFRLVYQVIDDQLIIAVVAVGK
RERSDVYHLASDRMR

Nucleotide

• Length: 288 bp

>T141512 NZ_CP059995:c4701654-4700899 [Pseudomonas aeruginosa]
GTGAGCGAGATCTGGCGACAGTGCAAGGGTGAGCGGCATATCCGACCGCTCCAGGGACGGCTGGTGCGGTTGGTGGAGAG
CCAGGAGCAGGTGGCGACCCTGCAATTGGTCGACACCCTGGAAGAGCAGGCATTGCTCGAGGAACTGCTCGAGTCGAGCA
AGCCGCCGGTGCCGGCGGACGCCGAGCCATTGCATTACCTGTTGAAGACCCCGTTCCGTTATCCGCCCTTGCGCTGGGGG
TCGCGGTTCGGCCGTCGCCACGAGCCAAGCCTGTTCTACGCCGCGTTGAAGCTGGAAACGGCCATGGCCGAAAGCGCGTA
TTACCGTTGCGTCCTGTGGAGTGGCATGGCAGTGCCGCCACCGAGCGGGAGGATTCTGTCCGAGCACGCTTCGTTCGAGG
CGGGCTGGAAGGTGGAGCGGGGAATCCGCCTGCAGGCAACGCCTTTCTCCGATCACGAGGCTGCGCTGACCGACATCGCC
GACTACCGCGCTCCCCAGGAACTGGGGAGCGCCATGCGCAGCGCCGGGGTGCAGGCATTCGAATACCGTTCGGCGCGTTG
CCCGGAGCGCGGCTGCAATGTCGCCCTGTTCACGCCCGCGGCCTTCACCGAAAAGCGTCCTCGCAACCTGACGCCCTGGC
TGTGCGAAACCACGGCCGGTTACGTGGCCTTCAAGCCGGCGCATGTACCGGGATCGCCGAAAATCTTCTCCTGGGAGCTG
TTCCTGGTGAACGGAAAGTTGCCGCATCCGGCGTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9270.67 Da
• Isoelectric Point: 4.1947

>AT141512 WP_058770150.1 NZ_CP045216:c1899347-1899096 [Pantoea dispersa]
MPNIILSDMSASVSELKKNPMATVNAGEGLPVAILNRNQPAFYCVPAQLYEQMLEALDDQELVKKVTERHQQPLIEVDLD
SFL

Nucleotide

• Length: 252 bp

>AT141512 NZ_CP059995:c4702156-4701788 [Pseudomonas aeruginosa]
ATGAGCGCTCTCATCAAGCAACGTCCCAGCGCCGATGCCGTCCTGGCCAAGGCCGTCCTCGCCGCGCGCGAGCAATTGGG
ACTGACGCAGCTCGAACTGGCCGGCATCGTCGGCGTCGATCGCAGCGCCATCAGCCGCTGGAAGACCCAGGGTCTGCGGG
TGGACAGCAAGACCGGCGAGCTGGCTCTGCTGCTGGTGCGGGTCTATCGCGCACTGTATGCCCTGTTCGGCGGGCAGCAG
GAGGACATGCGCCACTTCCTGCGCACGCCCAACCATCACCTGGCGGGCGAGCCGCTGGCACTGATGGGACAGGTGCAGGG
CCTGGTTCATGTGCTGGAATACCTCGATGCGATCCGCGGCAAGGTCTGA

Structures

Toxin

• AlphaFold DB: A0A246NE43