Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2807514..2807785 Replicon chromosome
Accession NZ_CP045209
Organism Escherichia coli strain 4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2807552..2807655 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2807514..2807785 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GC226_RS13670 2804671..2806110 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
GC226_RS13675 2806228..2806464 + 237 WP_001295499.1 YebV family protein -
GC226_RS13680 2806569..2806760 + 192 WP_001296140.1 YebW family protein -
GC226_RS13685 2806761..2807417 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2807514..2807785 + 272 - - Antitoxin
- 2807552..2807655 - 104 - - Toxin
GC226_RS13690 2807813..2808154 - 342 WP_000976492.1 YebY family protein -
GC226_RS13695 2808167..2809039 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
GC226_RS13700 2809043..2809417 - 375 WP_000204699.1 CopC domain-containing protein YobA -
GC226_RS13705 2809556..2809786 + 231 WP_000916763.1 DNA polymerase III subunit theta -
GC226_RS13710 2809888..2810544 + 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
GC226_RS13715 2810568..2811230 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T141464 NZ_CP045209:c2807655-2807552 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT141464 NZ_CP045209:2807514-2807785 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCTTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References