Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2346410..2346945 Replicon chromosome
Accession NZ_CP045202
Organism Dechloromonas sp. TW-R-39-2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GBK02_RS11300 Protein ID WP_203466772.1
Coordinates 2346410..2346673 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GBK02_RS11305 Protein ID WP_203466773.1
Coordinates 2346673..2346945 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GBK02_RS11285 2342828..2344570 - 1743 WP_203466769.1 type IV secretion system DNA-binding domain-containing protein -
GBK02_RS11290 2344570..2345037 - 468 WP_203466770.1 hypothetical protein -
GBK02_RS11300 2346410..2346673 - 264 WP_203466772.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GBK02_RS11305 2346673..2346945 - 273 WP_203466773.1 ribbon-helix-helix domain-containing protein Antitoxin
GBK02_RS11310 2347107..2348135 + 1029 WP_203466774.1 IS110 family transposase -
GBK02_RS11315 2348541..2348918 + 378 WP_203466775.1 transposase -
GBK02_RS11320 2348885..2349244 + 360 WP_203466776.1 IS66 family insertion sequence element accessory protein TnpB -
GBK02_RS11325 2349306..2350808 + 1503 WP_203469373.1 IS66 family transposase -
GBK02_RS11330 2350922..2351860 - 939 WP_203466777.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2307852..2352866 45014
- inside IScluster/Tn - - 2345819..2349244 3425


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-87)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-45)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10278.97 Da        Isoelectric Point: 9.5051

>T141418 WP_203466772.1 NZ_CP045202:c2346673-2346410 [Dechloromonas sp. TW-R-39-2]
MELKWSSKALSDLVRLYEFLGPANKQAAVRTVQALTKGPTILLTNPRIGEQLFEFEPREVRRLLIGHYEMRYEIQESTVY
MLRLWHT

Download         Length: 264 bp

>T141418 NZ_CP059958:c3763668-3763324 [Pectobacterium brasiliense]
ATGAAATCACTCTACTGGGTTGGCAGTAGCAAAAAGGATCTCCAATCGCTACCTGCAGATGTGCAGGATGTGTTCGGTTA
CGCACTTCATGTGGCTCAGACTGGTGGTAAGCACACTCAAGCCAAGCCGCTTAAAGGTTTTGGTGGTGCAGGCGTATTAG
AAGTCGTTGAGGATTATATCGGCGATACTTATCGCGCAGTCTACACCGTCAAATTTGGAGAGGCAGTGTACGTTCTACAT
ACTTTTCAGAAAAAATCGTCATCTGGAATTGCAACACCGAAATCCGATATGAACACCATCCGTGAGCGCCTGAAAACCGC
AGAAAACCATGCAAAAGGAGCATAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10112.45 Da        Isoelectric Point: 4.8380

>AT141418 WP_203466773.1 NZ_CP045202:c2346945-2346673 [Dechloromonas sp. TW-R-39-2]
MTQAISTKVLTAHVPLPLADKVDQMAERLERSRGWIMKQALSAWLSQEEERERLTREALADVEAGHVIDHQSVQAWADSL
GTDEPLPVPR

Download         Length: 273 bp

>AT141418 NZ_CP059958:c3763322-3763005 [Pectobacterium brasiliense]
ATGAGCCTGGATATTGAAGTCAGCAGCGGTAATGTGTACGCCGACCTTGGCAACGTGCATGCTGAAGATATGTTGGTCAA
AGCGCAGCTTGCCACACTGATTAGCTCAATCATCAAAAGCCGCCGTCTCACACAGGCAGAAGCAGCGAAGCTATTGGGCA
TGCCCCAACCCAAACTATCCAACTTATTACGTGGTCAGTTCAGGGGAATCAGTGAAACCAAAATGTTGGAATGCCTCACG
AAGCTGGGACGCGATATACAGATCGTGGTAGGGAAGCCGCGCCGCACGCCGGGTAGCGTTAAAGTCGTGTTTGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References