Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 623970..624468 Replicon chromosome
Accession NZ_CP045202
Organism Dechloromonas sp. TW-R-39-2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GBK02_RS03080 Protein ID WP_203468311.1
Coordinates 624208..624468 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GBK02_RS03075 Protein ID WP_203468310.1
Coordinates 623970..624218 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GBK02_RS03050 619315..620019 + 705 WP_203468308.1 ABC transporter ATP-binding protein -
GBK02_RS03055 620170..620652 - 483 WP_153151383.1 hypothetical protein -
GBK02_RS03060 621269..622138 + 870 WP_153151382.1 AraC family transcriptional regulator -
GBK02_RS03065 622209..622433 - 225 WP_203468309.1 hypothetical protein -
GBK02_RS03070 622441..623274 - 834 WP_203469279.1 site-specific integrase -
GBK02_RS03075 623970..624218 + 249 WP_203468310.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
GBK02_RS03080 624208..624468 + 261 WP_203468311.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GBK02_RS03085 624822..626363 - 1542 WP_203468312.1 DUF3987 domain-containing protein -
GBK02_RS03090 626528..626737 - 210 WP_203468313.1 transcriptional regulator -
GBK02_RS03095 627093..627971 + 879 WP_203468314.1 dienelactone hydrolase family protein -
GBK02_RS03100 628046..628480 + 435 WP_203468315.1 osmoprotectant transporter activator -
GBK02_RS03105 628506..629294 + 789 WP_203468316.1 class I SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9914.63 Da        Isoelectric Point: 10.1869

>T141417 WP_203468311.1 NZ_CP045202:624208-624468 [Dechloromonas sp. TW-R-39-2]
MSYELEFLEEALSEWQRLDGSIKAQFKKKLAERLVEPRLPSAKLSGHPDRYKIKLRSIGYRLVYEVLDGRLVVLVVAVGK
RDKNAV

Download         Length: 261 bp

>T141417 NZ_CP059958:3259382-3259798 [Pectobacterium brasiliense]
GTGAGTCGCTTGTTCATGCTGGATACCAATATCTGTTCCTTCATTATGCGGGAACACCCTGCGGAGGTGATTGAAAAGTT
GCAGCAGTGCACGCTGCGGCGTGATCGGATTGTGGTCTCTGCCATCACTTACGCTGAAATGCGTTTCGGGGCGGTTGGTA
AAAAAGCCTCGCCACGCCATATGCAACTGGTCGATGCTTTTTGCCGTCGGCTCGATGCGGTATTACCTTGGGATAGCGCC
GCAGTAGATGCCACCACGAAAATCAAAATCGAGCTAGCCGCCGCTGGCACACCTATTGGTCCAAACGATACGGCCATCGC
GGGCCATGCCATCAGCGCTAAGGCCATATTAGTCACCAATAATCTGAGAGAATTTGAGCGAGTACCGGGGCTGACGTTGG
AAGATTGGGTTAAATAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8984.34 Da        Isoelectric Point: 5.0789

>AT141417 WP_203468310.1 NZ_CP045202:623970-624218 [Dechloromonas sp. TW-R-39-2]
MAHQILSETAASISELKRNPMGTVAAGEGFPVAILNRNEPAFYCIPARAFESLMDRLEDLELNAIADARAGQKRVKVKLD
EL

Download         Length: 249 bp

>AT141417 NZ_CP059958:3259158-3259385 [Pectobacterium brasiliense]
ATGCGTATTGTTTCGGTATTTAAAAACGGTAACAACCGTGCCATTCGCTTGCCGCGTGATATGGACTTTGAAGGGGTCAA
CGAACTGGAGATTGTGCGTGAGGGAGATACCATCATGCTGCGTCCTGTTAAGCCCAATTGGCATTCGTTTTTGCAAGAAG
ATCGCGCTGACGCCGACTTTATGACAGAACGTCAGGATGTGGTCGAGGAGGGGAGATTCAAACTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References