Detailed information of TA system TA141414

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 2040522..2041146
• Replicon: chromosome
• Accession: NZ_CP045198
• Organism: Acinetobacter indicus strain TQ23

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: N9KY14
• Locus tag: GA693_RS10060
• Protein ID: WP_005180237.1
• Coordinates: 2040522..2040914 (-)
• Length: 131 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: GA693_RS10065
• Protein ID: WP_171065118.1
• Coordinates: 2040901..2041146 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GA693_RS10040	2035847..2038123	-	2277	WP_160240944.1	TRAP transporter large permease subunit	-
GA693_RS10045	2038304..2038876	-	573	WP_160240943.1	rhombosortase	-
GA693_RS10050	2038932..2040005	-	1074	WP_005180236.1	hypothetical protein	-
GA693_RS10055	2040195..2040374	+	180	WP_127801044.1	hypothetical protein	-
GA693_RS10060	2040522..2040914	-	393	WP_005180237.1	hypothetical protein	Toxin
GA693_RS10065	2040901..2041146	-	246	WP_171065118.1	succinate dehydrogenase assembly factor 2	Antitoxin
GA693_RS10070	2041342..2042514	+	1173	WP_005180239.1	acyl-CoA dehydrogenase family protein	-
GA693_RS10075	2042602..2044092	-	1491	WP_104470060.1	NAD(P)/FAD-dependent oxidoreductase	-
GA693_RS10080	2044291..2044656	-	366	WP_004754212.1	50S ribosomal protein L17	-
GA693_RS10085	2044676..2045683	-	1008	WP_005180245.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 131 a.a.
• Molecular weight: 14930.64 Da
• Isoelectric Point: 10.4540

>T141414 WP_005180237.1 NZ_CP045198:c2040914-2040522 [Acinetobacter indicus]
MSTAKRDFQLKPSRLALLFQLSLLILFSVLSFQLLHPLLWLLGLLLAAVSYYGFQRRSQLTALAHLDGAEWSLQFNSGSK
IQRGLLEHILDHQLYLVLYFHHAPVKSAVIWRDQVSFAEWKALKTLAKTI

Nucleotide

• Length: 393 bp

>T141414 NZ_CP059958:2574205-2574687 [Pectobacterium brasiliense]
ATGGGAATAACTGCGCCAGAGCCATTATCTTCCAGCCATAATCTTGCTGAATTTTGCAGCCAAGAACCGAGCTTGAATGA
ATGGCTAAAAAAGAAAGCGCTAAAAAATCATAGTGCAGGGATTTCTCGTGTATATGTGATTTGCGCTGAAGGCACACATC
AGGTGATTGGATATTATTGTTTATCAACAGGTAGCGTTCAGAGAAATACAGCGCCTGGTGCATATAGACGTAATGCCCCC
GAATCACTACCAGTCATTGTCCTTGGGCGGCTTGCCATTGATCAGGCGTATTCTGGTAAAGGTTTAGGTGTGGCTTTATT
AAAAGACGCGATATTTCGGACTGAGAATATTGCTTTGCAAGTGGGTGTGAGGGCATTAGTCGTTCACGCGCTGGATGAGA
ACGTGCGCAATTTCTACCTTAAATTCGCTTTTGATCCCTCGCCAGTGCAGCCCCTGATGCTACTCTATCCAATTAAAATT
TAG

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9758.15 Da
• Isoelectric Point: 4.9108

>AT141414 WP_171065118.1 NZ_CP045198:c2041146-2040901 [Acinetobacter indicus]
ISLEERKVIYRARRGLKEIDVYFDPYVKNYYLTADPEEKATFAALVEQEDPDLLDWFMEVSEPPRPEMRELIRKLKHYVH
G

Nucleotide

• Length: 246 bp

>AT141414 NZ_CP059958:2573936-2574214 [Pectobacterium brasiliense]
ATGAAACCTGAAACTAAAGAAGCGCCAATCAATATTCGGGCCAAAGCCTCCCAACGGGATTTGATCGATATGGCTGCAAA
CCTTGTGTCAAAATCGCGTACCGATTTTATGCTTGAAGCAGCCTGCCGCGAGGCGCAGGACATTTTGTTGGATCAACGTT
TGTTTATTTTGGATAACGAACAGTTTGACGAATTTTTGGCCGAGTTGGATGCGCCTATCACCGAAGAGCGTCAGGCTCGC
ATTAACGATCTAATGAGCCGCAAATCGCCATGGGAATAA

Structures

Toxin

• AlphaFold DB: N9KY14