Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 16617..17130 Replicon plasmid p23TQ-37k
Accession NZ_CP045196
Organism Acinetobacter indicus strain TQ23

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag GA693_RS00075 Protein ID WP_160246236.1
Coordinates 16867..17130 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GA693_RS00070 Protein ID WP_160246235.1
Coordinates 16617..16880 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GA693_RS00055 12320..15664 + 3345 WP_160246232.1 hypothetical protein -
GA693_RS00060 15687..15983 + 297 WP_160246233.1 phage holin family protein -
GA693_RS00065 15995..16381 + 387 WP_160246234.1 M15 family metallopeptidase -
GA693_RS00070 16617..16880 + 264 WP_160246235.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GA693_RS00075 16867..17130 + 264 WP_160246236.1 Txe/YoeB family addiction module toxin Toxin
GA693_RS00080 17165..17467 - 303 WP_160246237.1 hypothetical protein -
GA693_RS00085 17475..18131 - 657 WP_160246238.1 hypothetical protein -
GA693_RS00090 18351..18596 - 246 WP_114212213.1 helix-turn-helix domain-containing protein -
GA693_RS00095 18635..18952 - 318 WP_152342685.1 hypothetical protein -
GA693_RS00100 18967..19476 - 510 WP_160246239.1 antirestriction protein ArdA -
GA693_RS00105 20090..20521 + 432 WP_160246240.1 hypothetical protein -
GA693_RS00110 20769..21593 - 825 WP_160246241.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..37790 37790


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10642.10 Da        Isoelectric Point: 8.4926

>T141412 WP_160246236.1 NZ_CP045196:16867-17130 [Acinetobacter indicus]
MTNRNIEWTDHAWEEYLYWQTQDKKVLKRINALIKECQRTPFEGTGKPEPLKANLSGFWSRRIDEKHRLVYEVTDERISI
VQCRFHY

Download         Length: 264 bp

>T141412 NZ_CP059958:2422286-2423605 [Pectobacterium brasiliense]
ATGGCTGCTCTCGATGTTTACATGAACGGCTATCGGGTGGGGATTCTGACCAAAACGGGCAGTGGGGCACATCATTTTTC
CTATGATACGAACTGGCTCGGATTGCTGGGGAGTCGCCCCATTTCGCTTTCTATGCCGCTACGTCATCAGCCCTATCAAG
GCGATGAAGTTTATAACTTCTTCGACAATTTGTTGCCGGATAACCCGGATATCAGAAGACGGATTGTCGCCAGGCATCAT
ACGGATTCCACCCAACCGTTTGATCTGCTCGCTAAAGTGGGGCAAGACAGTGTCGGGGCGTTGCAATTAGTGCCGCAGGG
TACACCTGTGCACGATATAAAAAAGATCGAATATAAAACCTTATCCGAGCAGCAGCTTGAAAACATACTGACCGGATATT
TGTCCGATGCCCCGCTGGGTATGATTGATACTGAAGACGATTTTCGTATTTCTATCGCAGGTGCACAGGAAAAGACGGCA
TTGCTTTATCTGGATGATCGCTGGTGCCTGCCTCTCAATGTCACACCAACTACCCACATCATCAAGCTACCGATTGGTAA
AATCGAGAGTCACTCTTACTCAATTGATATGTCTGACAGCGTTGAAAATGAGTATCTGTGTTTGCTCATTGCCAAGGCAT
TTGGGCTGCCAGTGCCGCACTGTTTTATGATCAACGCTGGCAAGATAAAGGCGTTAGCGGTGGAGCGTTTTGATCGTAAA
TACGCCTCGGATGTCAGTTGGATTATGCGGCTACCACAAGAGGATTTTTGTCAGGTATTAAACGTTCCTTCCGCACTGAA
ATATGAAAATCATGGTGGACCGGGTATTTCCGCCATTATGTCGTTTCTATTGGGTTCGGTTTATCCAGAAAGAGATCGTT
ATCGCTTTATGCAGACTCAGGTACTGTTTTGGCTATTGGCTGCAACGGATGGTCATGCGAAAAACTTTTCCCTGTTTATT
GAATCTGAGGGACGATATCGACTCACGCCTTTCTATGACATTCTCTCTATGTATCCGGCGATGGGCGGACGGGGAATTGA
CCGCAGAGAGGCCAAACTGGCGATGGGATTAACTGGCTCAAGAGGCAAGAAATATGCGATTGAGCAGATCTTTCCCCGAC
ATTTTTTCCAGACGGCCAAGGTCGTTGGGTTCGCCAGAGAATCGATGGAAAACATTCTGGCGGAGTTTGCCCAGACCGTT
GATACCGTCATGACGACTGTTGGAAGTCAACTGCCTGTGGATTTTCCTACTCATATCAGTGAGGCAATTCTGGCCGGATT
GCAGGCCAGATCGAGACGGCTCATGAGCGGATGGGAGTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9793.98 Da        Isoelectric Point: 5.1085

>AT141412 WP_160246235.1 NZ_CP045196:16617-16880 [Acinetobacter indicus]
MHVFTYTDARNNLKSVLDKVVDDADVAVITRKEGSHAVVMGQEHYDSLMETLYLLSSPNNAARLNESIAQLRASKTKRKE
LIEDDES

Download         Length: 264 bp

>AT141412 NZ_CP059958:2422017-2422286 [Pectobacterium brasiliense]
ATGATGAAGATCACCAACAGCAAGCAGCTTAGCAGCTATCTGAAAGATGTTCGTATCACGCAGAAGCTTTCACAAGGGAA
AGTGGCCAGTAAAGTGGGTATTCGCCAGGATACGGTATCCAGTTTCGAGCAACATCCTGATTCCACTAAGTTGGAAACCT
TCTTTAAAATCCTGTCGGCATTGAATTTAGAACTTACTGTTACGCCCAGGAATGTGGACACCACCAATAACGAAGCCTCT
GTTGCATCATCCTGGAAGGAAGAATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References