Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1951228..1951373 Replicon chromosome
Accession NZ_CP045193
Organism Klebsiella pneumoniae strain YML0508

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1951264..1951366 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1951228..1951373 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F8E20_RS09335 1946358..1948418 + 2061 WP_004151449.1 oligopeptidase B -
F8E20_RS09340 1948422..1949081 - 660 WP_002911407.1 exodeoxyribonuclease X -
F8E20_RS09345 1949160..1949390 - 231 WP_002911406.1 DNA polymerase III subunit theta -
F8E20_RS09350 1949503..1949877 + 375 WP_004151448.1 CopC domain-containing protein YobA -
F8E20_RS09355 1949881..1950750 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
F8E20_RS09360 1950767..1951105 + 339 WP_002911404.1 YebY family protein -
- 1951228..1951373 - 146 - - Antitoxin
- 1951264..1951366 + 103 - - Toxin
F8E20_RS09365 1951741..1951884 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
F8E20_RS09370 1951989..1952957 - 969 WP_004151446.1 VirK/YbjX family protein -
F8E20_RS09375 1953114..1953767 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
F8E20_RS09380 1953764..1953955 - 192 WP_002911395.1 YebW family protein -
F8E20_RS09385 1954053..1954292 - 240 WP_002911393.1 YebV family protein -
F8E20_RS09390 1954408..1955841 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T141396 NZ_CP045193:1951264-1951366 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT141396 NZ_CP045193:c1951373-1951228 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References