Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2416806..2416900 Replicon chromosome
Accession NZ_CP045149
Organism Yersinia pestis strain SCPM-O-DNA-18 (I-3113)

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2416807..2416900 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2416806..2416900 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GCK70_RS11565 2411999..2414077 - 2079 WP_002211100.1 flagellar biosynthesis protein FlhA -
GCK70_RS11570 2414077..2415237 - 1161 WP_002211099.1 flagellar type III secretion system protein FlhB -
GCK70_RS11575 2415769..2416227 + 459 WP_002211098.1 hypothetical protein -
GCK70_RS11580 2416221..2416547 + 327 WP_002211097.1 DUF1493 family protein -
- 2416806..2416900 + 95 - - Antitoxin
- 2416807..2416900 - 94 - - Toxin
GCK70_RS11590 2417070..2417411 - 342 WP_002211095.1 YebY family protein -
GCK70_RS11595 2417508..2418392 - 885 WP_002211094.1 copper homeostasis membrane protein CopD -
GCK70_RS11600 2418395..2418781 - 387 WP_002211093.1 CopC domain-containing protein YobA -
GCK70_RS11605 2419178..2419687 - 510 WP_002211092.1 non-heme ferritin -
GCK70_RS11610 2420088..2420318 + 231 WP_002211091.1 DNA polymerase III subunit theta -
GCK70_RS11615 2420378..2421328 - 951 WP_002211090.1 prolyl aminopeptidase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 94 bp

>T141303 NZ_CP045149:c2416900-2416807 [Yersinia pestis]
TAAGCCTACATTAATACCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATCAGGAATCGTA
TTCGGTCTTTTTTT

Antitoxin


Download         Length: 95 bp

>AT141303 NZ_CP045149:2416806-2416900 [Yersinia pestis]
TAAAAAAAGACCGAATACGATTCCTGATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGT
ATTAATGTAGGCTTA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References