Detailed information of TA system TA141271

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): NpoTA/ParE(toxin)
• Location: 2161428..2162543
• Replicon: chromosome
• Accession: NZ_CP045135
• Organism: Acinetobacter indicus strain XG01

Toxin (Protein)

• Gene name: NpoT
• Uniprot ID: V2U6R6
• Locus tag: GA636_RS10340
• Protein ID: WP_016658124.1
• Coordinates: 2161428..2161592 (-)
• Length: 55 a.a.

Antitoxin (Protein)

• Gene name: NpoA
• Uniprot ID: -
• Locus tag: GA636_RS10345
• Protein ID: WP_160232466.1
• Coordinates: 2161674..2162543 (-)
• Length: 290 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GA636_RS10325	2157407..2158429	+	1023	WP_104470196.1	ferredoxin reductase	-
GA636_RS10330	2158453..2159610	+	1158	WP_171293312.1	fatty acid desaturase	-
GA636_RS10335	2159911..2161329	+	1419	WP_160232465.1	iron-containing redox enzyme family protein	-
GA636_RS10340	2161428..2161592	-	165	WP_016658124.1	hypothetical protein	Toxin
GA636_RS10345	2161674..2162543	-	870	WP_160232466.1	SDR family oxidoreductase	Antitoxin
GA636_RS10350	2162646..2162885	-	240	WP_075166617.1	DUF2171 domain-containing protein	-
GA636_RS10355	2163544..2164785	+	1242	WP_016658127.1	MFS transporter	-
GA636_RS10360	2165223..2165630	+	408	WP_160232467.1	KGG domain-containing protein	-
GA636_RS10365	2165819..2166268	-	450	WP_005178047.1	cyanase	-
GA636_RS10370	2166561..2167370	+	810	WP_005178046.1	formate/nitrite transporter family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 55 a.a.
• Molecular weight: 6182.76 Da
• Isoelectric Point: 10.1466

>T141271 WP_016658124.1 NZ_CP045135:c2161592-2161428 [Acinetobacter indicus]
MSRGDKSAYTDKQKRQARHIIESEKERGHSEEEAERIGWSTVNKQDGGGKKKSH

Nucleotide

• Length: 165 bp

>T141271 NZ_CP059908:c102240-102034 [Escherichia coli]
ATGAAGTACCTTAACACTACTGATTGTAGCCTCTTCTTTGCTGAGAGGTCAAAGTTTATGACGAAATATGCCCTTATCGG
GTTGCTCGCCGTGTGCGCCACGGTGTTGTGTTTTTCACTGATATTCAGGGAACGGTTATGTGAGCTGAATATTCACAGAG
GAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA

Antitoxin

Protein

• Length: 290 a.a.
• Molecular weight: 31903.02 Da
• Isoelectric Point: 4.8505

>AT141271 WP_160232466.1 NZ_CP045135:c2162543-2161674 [Acinetobacter indicus]
MNHYPDSPSPQEKQEHQPGVQYKMTPEPEIIKNHYQGSQKLKDKVALITGGDSGIGRSVAVLFAREGANIIIPYLEEDQD
AQDTKRLVEQEGCQCLLIQCDLRQHAAVQQMVDLALQQFPHINILVNNAAVQYPQKTIEDINPEQLHKTFETNLYPLFYV
TQLLIPQMQPGDSIINTTSITSYQGHNELIDYASTKGAITAFTRSLSTNLLKNKTGIRVNGVAPGPIWTPLIPSSFDEEQ
LKGFGEDTPMGRMGQPSEVAPAYLFLASDEASYISGQVIHVNGGTIVNG

Nucleotide

• Length: 870 bp

>AT141271 NZ_CP059908:102227-102288 [Escherichia coli]
TTAAGGTACTTCATGCAGACCTCACGAGTTAATGGATTAACGAGTGGGGTCTTCGCATTTCT

Structures

Toxin

• AlphaFold DB: V2U6R6