Detailed information of TA system TA141270

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 1081467..1082091
• Replicon: chromosome
• Accession: NZ_CP045135
• Organism: Acinetobacter indicus strain XG01

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: N9KY14
• Locus tag: GA636_RS05320
• Protein ID: WP_005180237.1
• Coordinates: 1081699..1082091 (+)
• Length: 131 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: GA636_RS05315
• Protein ID: WP_171065118.1
• Coordinates: 1081467..1081712 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GA636_RS05295	1076929..1077936	+	1008	WP_005180245.1	DNA-directed RNA polymerase subunit alpha	-
GA636_RS05300	1077956..1078321	+	366	WP_004754212.1	50S ribosomal protein L17	-
GA636_RS05305	1078521..1080011	+	1491	WP_005180241.1	NAD(P)/FAD-dependent oxidoreductase	-
GA636_RS05310	1080099..1081271	-	1173	WP_075167404.1	acyl-CoA dehydrogenase family protein	-
GA636_RS05315	1081467..1081712	+	246	WP_171065118.1	succinate dehydrogenase assembly factor 2	Antitoxin
GA636_RS05320	1081699..1082091	+	393	WP_005180237.1	hypothetical protein	Toxin
GA636_RS05325	1082239..1082418	-	180	WP_127801044.1	hypothetical protein	-
GA636_RS05330	1082608..1083681	+	1074	WP_016658537.1	hypothetical protein	-
GA636_RS05335	1083737..1084309	+	573	WP_127799341.1	rhombosortase	-
GA636_RS05340	1084490..1086766	+	2277	WP_127799343.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 131 a.a.
• Molecular weight: 14930.64 Da
• Isoelectric Point: 10.4540

>T141270 WP_005180237.1 NZ_CP045135:1081699-1082091 [Acinetobacter indicus]
MSTAKRDFQLKPSRLALLFQLSLLILFSVLSFQLLHPLLWLLGLLLAAVSYYGFQRRSQLTALAHLDGAEWSLQFNSGSK
IQRGLLEHILDHQLYLVLYFHHAPVKSAVIWRDQVSFAEWKALKTLAKTI

Nucleotide

• Length: 393 bp

>T141270 NZ_CP059908:c98650-98363 [Escherichia coli]
ATGACTTATACAGTAAAATTCAGGGATGATGCGCTCAAAGAATGGCTGAAACTGGATAAATCCATTCAACAGCAGTTTGC
GAAAAAACTAAAGAAATGCAGCGAAAATCCTCATATTCCTTCCGCAAAACTGCGTGGATTAAAAGACTGCTACAAAATCA
AACTTCGCGCATCGGGGTTTCGTCTGGTCTATCAGGTTATTGATGACATGCTAATTATTGCGGTTGTCGCGGTAGGTAAA
CGTGAACGTAGTAACGTTTATAATCTCGCCAGTGAGAGAATGAGATAG

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9758.15 Da
• Isoelectric Point: 4.9108

>AT141270 WP_171065118.1 NZ_CP045135:1081467-1081712 [Acinetobacter indicus]
ISLEERKVIYRARRGLKEIDVYFDPYVKNYYLTADPEEKATFAALVEQEDPDLLDWFMEVSEPPRPEMRELIRKLKHYVH
G

Nucleotide

• Length: 246 bp

>AT141270 NZ_CP059908:c98898-98647 [Escherichia coli]
ATGCCTAACATCATTCTGTCTGACACCAGTGCAAGTGTCAGTGAACTGAAAAAAAATCCTATGGCTACAGTCAGTGCCGG
AGATGGTTATCCTGTCGCCATTCTTAACCGGAATCAGCCGGCATTCTACTGTGTGCCTGCGGAACTCTATGAAAGGATGC
TTGATGCGCTGGATGACCAGGAACTGGTGAAACTGGTTACTGAACGCAGCAATCAGCCACTGCATGATGTGGACCTGGAC
AGTTATTTATGA

Structures

Toxin

• AlphaFold DB: N9KY14