Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 2904846..2905374 Replicon chromosome
Accession NZ_CP045129
Organism Acinetobacter indicus strain TQ04

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GA660_RS13865 Protein ID WP_000221359.1
Coordinates 2904846..2905139 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GA660_RS13870 Protein ID WP_160232242.1
Coordinates 2905129..2905374 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GA660_RS13845 2900646..2901736 + 1091 WP_085940648.1 IS4-like element ISAba1 family transposase -
GA660_RS13850 2901779..2902819 - 1041 WP_160241744.1 IS481 family transposase -
GA660_RS13855 2903094..2904226 + 1133 Protein_2671 IS3-like element ISAba14 family transposase -
GA660_RS13860 2904362..2904772 - 411 WP_160241745.1 PH domain-containing protein -
GA660_RS13865 2904846..2905139 - 294 WP_000221359.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GA660_RS13870 2905129..2905374 - 246 WP_160232242.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
GA660_RS13875 2905457..2905612 - 156 WP_160241746.1 hypothetical protein -
GA660_RS13880 2905615..2905785 - 171 Protein_2676 transposase -
GA660_RS13885 2906180..2907115 + 936 WP_160241747.1 HNH endonuclease -
GA660_RS13890 2907445..2907816 - 372 WP_004726814.1 hypothetical protein -
GA660_RS13895 2907938..2908642 - 705 WP_001067784.1 IS6-like element IS1006 family transposase -
GA660_RS13900 2908739..2909032 + 294 Protein_2680 IS5/IS1182 family transposase -
GA660_RS13905 2909164..2909373 - 210 WP_160241748.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn sul2 / tet(X3) / aph(6)-Id / aph(3'')-Ib - 2889463..2908642 19179


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-71)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11291.58 Da        Isoelectric Point: 10.6284

>T141261 WP_000221359.1 NZ_CP045129:c2905139-2904846 [Acinetobacter indicus]
MTYKLLRHKDFTAEWEKLPVAIRDQFKKKLAKVIKQPHIPKNMLRGDLAGCYKIKLLKAGVRLVYQVKDDQVVILLITVG
KRADSIVYDEAKKRIKD

Download         Length: 294 bp

>T141261 NZ_CP059907:3239326-3239502 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTGGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCAAGGGCGACGCAGTGTCATGCCGCGTCACCCCAGTGATGAGATAAAAGAACCATTGCGTAAAGCAATCCTGAAGC
AACTCGGTTTAAATTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9265.64 Da        Isoelectric Point: 4.3142

>AT141261 WP_160232242.1 NZ_CP045129:c2905374-2905129 [Acinetobacter indicus]
MATVNFRVDEALKEKSYSILKEQGITPTDFFTSILEYVATTGKLPVKKALLSEEDEELLALVRKRINDPKEMFEEVTLDD
L

Download         Length: 246 bp

>AT141261 NZ_CP059907:3239546-3239962 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACTCCTGCGCCGGAAGGCGGTTATGTGGTTTCTTTTGTAGATATCCCTGAAGCGTTGAC
GCAGGGAGAAACTGTTGCTGAAGCGATGGAAGCAGCAAAAGATGCCTTACTCACCGCATTTGATTTTTATTTTGAAGATA
ATGAGCTAATCCCGTTGCCTTCGCCATTAACTAACAACGATCACTTTATTGAAGTGCCTTTAAGTATCGCCTCTAAAGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGACGAATTGGCAAACCTAAACAGGAGAT
TACTCGCTTATTTAACTTGCACCATGCTACAAAAATCGACGCCGTCCAGCTTGCGGCTAAGGCGCTTGGCAAAGAGTTAT
CACTGGTGATGGTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References