Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 472400..473024 Replicon chromosome
Accession NZ_CP045129
Organism Acinetobacter indicus strain TQ04

Toxin (Protein)


Gene name cptA Uniprot ID N9KY14
Locus tag GA660_RS02335 Protein ID WP_005180237.1
Coordinates 472632..473024 (+) Length 131 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag GA660_RS02330 Protein ID WP_171065118.1
Coordinates 472400..472645 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GA660_RS02310 467863..468870 + 1008 WP_005180245.1 DNA-directed RNA polymerase subunit alpha -
GA660_RS02315 468890..469255 + 366 WP_004754212.1 50S ribosomal protein L17 -
GA660_RS02320 469454..470944 + 1491 WP_104470060.1 NAD(P)/FAD-dependent oxidoreductase -
GA660_RS02325 471032..472204 - 1173 WP_005180239.1 acyl-CoA dehydrogenase family protein -
GA660_RS02330 472400..472645 + 246 WP_171065118.1 succinate dehydrogenase assembly factor 2 Antitoxin
GA660_RS02335 472632..473024 + 393 WP_005180237.1 hypothetical protein Toxin
GA660_RS02340 473172..473351 - 180 WP_127801044.1 hypothetical protein -
GA660_RS02345 473541..474614 + 1074 WP_005180236.1 hypothetical protein -
GA660_RS02350 474670..475242 + 573 WP_160240943.1 rhombosortase -
GA660_RS02355 475423..477699 + 2277 WP_160240944.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14930.64 Da        Isoelectric Point: 10.4540

>T141259 WP_005180237.1 NZ_CP045129:472632-473024 [Acinetobacter indicus]
MSTAKRDFQLKPSRLALLFQLSLLILFSVLSFQLLHPLLWLLGLLLAAVSYYGFQRRSQLTALAHLDGAEWSLQFNSGSK
IQRGLLEHILDHQLYLVLYFHHAPVKSAVIWRDQVSFAEWKALKTLAKTI

Download         Length: 393 bp

>T141259 NZ_CP059907:c2995281-2995174 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGGATTATTACCGCAGTGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9758.15 Da        Isoelectric Point: 4.9108

>AT141259 WP_171065118.1 NZ_CP045129:472400-472645 [Acinetobacter indicus]
ISLEERKVIYRARRGLKEIDVYFDPYVKNYYLTADPEEKATFAALVEQEDPDLLDWFMEVSEPPRPEMRELIRKLKHYVH
G

Download         Length: 246 bp

>AT141259 NZ_CP059907:2995334-2995395 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB N9KY14

Antitoxin

Source ID Structure

References