Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 293815..294343 Replicon chromosome
Accession NZ_CP045129
Organism Acinetobacter indicus strain TQ04

Toxin (Protein)


Gene name relE Uniprot ID N9N871
Locus tag GA660_RS01390 Protein ID WP_000221358.1
Coordinates 294050..294343 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GA660_RS01385 Protein ID WP_104988060.1
Coordinates 293815..294060 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GA660_RS01365 289378..289629 + 252 WP_104988057.1 DUF4041 domain-containing protein -
GA660_RS01370 290514..292379 + 1866 WP_104988058.1 copper resistance system multicopper oxidase -
GA660_RS01375 292366..292704 + 339 WP_104988059.1 hypothetical protein -
GA660_RS01380 292691..293635 + 945 WP_004668309.1 copper resistance protein B -
GA660_RS01385 293815..294060 + 246 WP_104988060.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
GA660_RS01390 294050..294343 + 294 WP_000221358.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GA660_RS01395 294472..294801 - 330 WP_004641881.1 four-helix bundle copper-binding protein -
GA660_RS01400 295077..296138 + 1062 Protein_271 IS3 family transposase -
GA660_RS01405 296851..297414 + 564 WP_005180661.1 alkyl hydroperoxide reductase subunit C -
GA660_RS01410 297616..298491 + 876 WP_160240883.1 pirin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 244500..294343 49843


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-71)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11292.52 Da        Isoelectric Point: 10.4753

>T141258 WP_000221358.1 NZ_CP045129:294050-294343 [Acinetobacter indicus]
MTYKLLRHKDFTAEWEKLPVAIRDQFKKKLAKVIEQPHIPKNMLRGDLAGCYKIKLLKAGVRLVYQVKDDQVVILLITVG
KRADSIVYDEAKKRIKD

Download         Length: 294 bp

>T141258 NZ_CP059907:2924456-2924558 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9279.66 Da        Isoelectric Point: 4.3142

>AT141258 WP_104988060.1 NZ_CP045129:293815-294060 [Acinetobacter indicus]
MATVNFRIDEALKEKSYSILKEQGITPTDFFTSILEYVATTGKLPVKKALLSEEDEELLALVRKRINDPKEMFEEVTLDD
L

Download         Length: 246 bp

>AT141258 NZ_CP059907:c2924596-2924328 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6A1RKP4

Antitoxin

Source ID Structure

References