Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1(toxin)
Location 5393275..5393849 Replicon chromosome
Accession NZ_CP045118
Organism Pseudomonas sp. SCB32

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GA645_RS24660 Protein ID WP_152226338.1
Coordinates 5393275..5393640 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GA645_RS24665 Protein ID WP_152226340.1
Coordinates 5393634..5393849 (-) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GA645_RS24645 5389211..5390107 + 897 WP_152226334.1 sigma-54-dependent transcriptional regulator -
GA645_RS24650 5390668..5392626 + 1959 WP_152228301.1 choline BCCT transporter BetT -
GA645_RS24655 5392669..5393145 - 477 WP_152226336.1 2TM domain-containing protein -
GA645_RS24660 5393275..5393640 - 366 WP_152226338.1 type II toxin-antitoxin system VapC family toxin Toxin
GA645_RS24665 5393634..5393849 - 216 WP_152226340.1 ribbon-helix-helix protein, CopG family Antitoxin
GA645_RS24670 5393956..5395995 - 2040 WP_152226342.1 oligopeptide transporter, OPT family -
GA645_RS24675 5396327..5397163 - 837 WP_152226344.1 taurine dioxygenase -
GA645_RS24680 5397249..5398067 - 819 WP_152226346.1 ABC transporter permease subunit -
GA645_RS24685 5398057..5398848 - 792 WP_152226349.1 ATP-binding cassette domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-104)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-38)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13700.87 Da        Isoelectric Point: 5.2358

>T141248 WP_152226338.1 NZ_CP045118:c5393640-5393275 [Pseudomonas sp. SCB32]
MVRVLFDTNILIDYLNGHGQARDELALYSDRAISIITWMEVMIGVTPDTEAATRAFLSSFTLLALDERIAERAVEVRQRL
RVKLPDAIIKATAEVEGRLLVTRNIKDFAESEPGVRLPYRL

Download         Length: 366 bp

>T141248 NZ_CP059907:942976-943083 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGCATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8333.30 Da        Isoelectric Point: 4.6128

>AT141248 WP_152226340.1 NZ_CP045118:c5393849-5393634 [Pseudomonas sp. SCB32]
MRTLVDIPAEYLERLNDISERQQQSRASIIREAIAEYLVNHARADADAAFGLWKERQVDGLAYQEKVREEW

Download         Length: 216 bp

>AT141248 NZ_CP059907:c942919-942861 [Escherichia coli]
TCAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References