Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 4831007..4831520 Replicon chromosome
Accession NZ_CP045118
Organism Pseudomonas sp. SCB32

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GA645_RS22020 Protein ID WP_152225427.1
Coordinates 4831236..4831520 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GA645_RS22015 Protein ID WP_152225425.1
Coordinates 4831007..4831246 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GA645_RS22005 4828180..4829400 - 1221 WP_152225421.1 exonuclease subunit SbcD -
GA645_RS22010 4829534..4830898 + 1365 WP_152225423.1 C4-dicarboxylate ABC transporter substrate-binding protein -
GA645_RS22015 4831007..4831246 + 240 WP_152225425.1 ribbon-helix-helix protein, CopG family Antitoxin
GA645_RS22020 4831236..4831520 + 285 WP_152225427.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GA645_RS22025 4831643..4832650 + 1008 WP_152225429.1 nucleoid-associated protein YejK -
GA645_RS22030 4833101..4833967 + 867 WP_152225431.1 hypothetical protein -
GA645_RS22035 4833948..4834883 - 936 WP_152225433.1 glutathione S-transferase family protein -
GA645_RS22040 4834947..4835249 - 303 WP_152225435.1 GIY-YIG nuclease family protein -
GA645_RS22045 4835246..4835947 - 702 WP_152225437.1 glutathione S-transferase C-terminal domain-containing protein -
GA645_RS22050 4836020..4836502 - 483 WP_152225439.1 nuclear transport factor 2 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10862.54 Da        Isoelectric Point: 11.1310

>T141247 WP_152225427.1 NZ_CP045118:4831236-4831520 [Pseudomonas sp. SCB32]
MRIEWLRKALRNLDDEATYIAQDNPAAARAFVIAVVADVERLALNPASGREGRVPGTREWAMTSHPYLIPYRIRDGRLQV
LRIFHTRRLPPAQW

Download         Length: 285 bp

>T141247 NZ_CP059907:942493-942600 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGCATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8703.71 Da        Isoelectric Point: 4.1348

>AT141247 WP_152225425.1 NZ_CP045118:4831007-4831246 [Pseudomonas sp. SCB32]
MPVMSLRLSDDQSETLAKLAHATGRSKNFLAAQALEEYLVRESWQIGEILEAIVEADAGDFASDAEVKAILDKWTHDAD

Download         Length: 240 bp

>AT141247 NZ_CP059907:c942436-942378 [Escherichia coli]
TCAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References