Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 55375..55880 Replicon chromosome
Accession NZ_CP045118
Organism Pseudomonas sp. SCB32

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag GA645_RS00275 Protein ID WP_152218837.1
Coordinates 55375..55656 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag GA645_RS00280 Protein ID WP_152218839.1
Coordinates 55653..55880 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GA645_RS00255 52376..53326 + 951 WP_152218829.1 alpha/beta hydrolase -
GA645_RS00260 53330..53785 - 456 WP_152218831.1 GNAT family N-acetyltransferase -
GA645_RS00265 53828..54745 - 918 WP_152218833.1 LysR family transcriptional regulator -
GA645_RS00270 54843..55130 + 288 WP_152218835.1 DUF2218 domain-containing protein -
GA645_RS00275 55375..55656 - 282 WP_152218837.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GA645_RS00280 55653..55880 - 228 WP_152218839.1 CopG family ribbon-helix-helix protein Antitoxin
GA645_RS00285 56143..57528 + 1386 WP_152218840.1 sodium:solute symporter -
GA645_RS00290 57556..58512 + 957 WP_152218842.1 agmatinase -
GA645_RS00295 58587..59514 + 928 Protein_58 LysR family transcriptional regulator -
GA645_RS00300 59511..60230 + 720 WP_152218844.1 phytanoyl-CoA dioxygenase family protein -
GA645_RS00305 60245..60646 + 402 WP_152218846.1 GFA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-87)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10462.88 Da        Isoelectric Point: 6.7235

>T141240 WP_152218837.1 NZ_CP045118:c55656-55375 [Pseudomonas sp. SCB32]
MSLQWTHKAATDLDAIYDHYVVLIGPEKALRAIQDIVEQVRPLANLDQSSSGVPSEVPGVRELPVERWPYHAAYRVKGRS
VQILRIDRVDNSG

Download         Length: 282 bp

>T141240 NZ_CP059901:659092-659394 [Mumia sp. ZJ1417]
ATGCGTCCGATCCACATGGCGCGTCTCGACAAGGCGCGGCCGGTGTTGATCCTCACCCGCGAGGCCGTGCGGCCCTACCT
CACCCGTGTGACCGTCGCTCCGATCACCAGCACCATCCGCGGCTTGTCGACCGAGGTGGAGGTAGGCCCCGTAAACGGAC
TGGACCACGTCAGCGTCGTGAGCTGCGACAACATCGTGACCGTCCCGGTGGCCTCGGTGGGCCGACAGCTTGGCTTCCTG
CTCGACTCCCAGGAGGCCGAGCTGGCGGACGCGGTCCGCGCCGCCTTCGACCTGGACTGGTAG

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8249.26 Da        Isoelectric Point: 5.4762

>AT141240 WP_152218839.1 NZ_CP045118:c55880-55653 [Pseudomonas sp. SCB32]
VTTVVSFRADDALVAALDQLARATHRDRPYHLRQALTQYLERQSWHVAAIDEGVADADAGLLLEHAAIEAKWGLA

Download         Length: 228 bp

>AT141240 NZ_CP059901:658856-659092 [Mumia sp. ZJ1417]
ATGAGCACCCAGATCGCGGTACGCCTGGACGAGGAGCTTGTCGAGTTCGTCGATGCCCTCGTACGCCGCGGCGAGGCGTC
TAGTCGTGCAGCGGTGGTCGCTCGGGCACTCGAACGGGAGCGGCGTCGCAAGACCGCAGAGCGCGATGCGGCAATCCTCG
CTGCGGCCCGAACGGACGCGGACATGGACGATCTCGCCGAGTTCGCCTCCCGCCTTCCGATGGACGACATCGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References