Detailed information of TA system TA141234

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 3296351..3297000
• Replicon: chromosome
• Accession: NZ_CP045103
• Organism: Acinetobacter johnsonii strain AJ413

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: GBN93_RS15805
• Protein ID: WP_234964880.1
• Coordinates: 3296351..3296737 (-)
• Length: 129 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: N9CU98
• Locus tag: GBN93_RS15810
• Protein ID: WP_004977895.1
• Coordinates: 3296743..3297000 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GBN93_RS15790 (GBN93_15845)	3291684..3293966	-	2283	WP_234964877.1	TRAP transporter large permease subunit	-
GBN93_RS15795 (GBN93_15850)	3294149..3294721	-	573	WP_234964878.1	rhombosortase	-
GBN93_RS15800	3294793..3295830	-	1038	WP_234964879.1	hypothetical protein	-
GBN93_RS15805 (GBN93_15865)	3296351..3296737	-	387	WP_234964880.1	hypothetical protein	Toxin
GBN93_RS15810 (GBN93_15870)	3296743..3297000	-	258	WP_004977895.1	succinate dehydrogenase assembly factor 2	Antitoxin
GBN93_RS15815 (GBN93_15875)	3297193..3298365	+	1173	WP_234964881.1	acyl-CoA dehydrogenase family protein	-
GBN93_RS15820	3298400..3298846	-	447	WP_234964882.1	alpha/beta hydrolase	-
GBN93_RS15825	3298867..3299190	-	324	WP_234964883.1	hypothetical protein	-
GBN93_RS15830 (GBN93_15885)	3299329..3300819	-	1491	WP_234964884.1	NAD(P)/FAD-dependent oxidoreductase	-
GBN93_RS15835 (GBN93_15890)	3301015..3301380	-	366	WP_004691290.1	50S ribosomal protein L17	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (5-127)

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 129 a.a.
• Molecular weight: 15350.33 Da
• Isoelectric Point: 10.4419

>T141234 WP_234964880.1 NZ_CP045103:c3296737-3296351 [Acinetobacter johnsonii]
MEHRHFQLKPSRLAYVFQLSIYAVLMLVLYQLLPFGLWLIALVAGFVLYLFFLRGPQHFQLQHLDGRDWSLSLQKQTNVQ
RVQISHIVDHRAYIVIYFQHFRAKPMLVWCDQLPITQWKALKILTKMQ

Nucleotide

• Length: 387 bp

>T141234 NZ_CP059900:c3838634-3838374 [Tomitella sp. HY172]
ATGAGGCTGGTCTGGGACGAGGCGGCGTGGGACGACTACCTGTGGTGGCAGGCGCAGGACCGCAAGACGCTCAAGCGCAT
CAACGCGCTGATCCGCGATATCCAGCGCAACGGCAATGAGGGCATCGGGAAGCCCGAGCAGCTCAGACACGGATTCCAGG
GCTACTGGTCGCGGCGGATCACCCTGGAGCATCGGTTGGTGTACAAAATCATCGGCGACGAGATCCGGTTCGCCGCATGC
CGATACCACTACGGGGAGTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10181.71 Da
• Isoelectric Point: 4.7119

>AT141234 WP_004977895.1 NZ_CP045103:c3297000-3296743 [Acinetobacter johnsonii]
MTEEMSLEERKVIYRARRGLKEIDVYFDPYVKNYYLQADPAEKAMFAALVEQEDPDLLDWFMEVSEPPRPEMKTLIQKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT141234 NZ_CP059900:c3838882-3838631 [Tomitella sp. HY172]
GTGCGGACGATCTCTTATTCGGAATCACGGGCGCGGTACGCGGAAACGCTCGATAGCGTCATCGACGATCGCGAGGAGGT
CATCGTCACGCGTGCGGGACGCGACCCGGTGGTGATGGTGGCGCTCGACGAGTACGAGTCCCTCAAGGAGACGGCGTACC
TGCTCAAGAGTCCCGAGAATGCGCGTCGCCTCCTCGCCTCCATCAAGCGACTCGAATCGGGGGAAGGGGTCGAGCGGGAT
CTCGCCGAATGA

Structures

Antitoxin

• AlphaFold DB: N9CU98