141228

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 2824936..2825735 Replicon chromosome
Accession NZ_CP045098
Organism Pectobacterium carotovorum strain ZM1

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag GBN63_RS12670 Protein ID WP_201963705.1
Coordinates 2824936..2825355 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag GBN63_RS12675 Protein ID WP_161509016.1
Coordinates 2825352..2825735 (-) Length 128 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GBN63_RS12650 (GBN63_12715) 2820042..2820683 + 642 WP_010281304.1 uridine kinase -
GBN63_RS12655 (GBN63_12720) 2820795..2821376 + 582 WP_005974037.1 dCTP deaminase -
GBN63_RS12660 (GBN63_12725) 2821440..2823275 + 1836 WP_239766155.1 outer membrane assembly protein AsmA -
GBN63_RS12665 (GBN63_12730) 2823540..2824892 + 1353 WP_014914716.1 anaerobic C4-dicarboxylate transporter DcuC -
GBN63_RS12670 (GBN63_12735) 2824936..2825355 - 420 WP_201963705.1 DUF86 domain-containing protein Toxin
GBN63_RS12675 (GBN63_12740) 2825352..2825735 - 384 WP_161509016.1 nucleotidyltransferase domain-containing protein Antitoxin
GBN63_RS12680 (GBN63_12745) 2825849..2827435 - 1587 WP_239766157.1 TerC family protein -
GBN63_RS12685 (GBN63_12750) 2828185..2829264 + 1080 WP_039506648.1 UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase -
GBN63_RS12690 (GBN63_12755) 2829390..2830526 + 1137 WP_039506650.1 polysaccharide export protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(13-130)

Antitoxin

Polymerase beta, nucleotidyltransferase

(4-93)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15994.33 Da        Isoelectric Point: 7.3843

>T141228 WP_201963705.1 NZ_CP045098:c2825355-2824936 [Pectobacterium carotovorum]
MTDILLNKSSTIQRCLRRIREEFDTEEGFRQNFTKQDSVILNIQRACEAAIDIANYLIRIKQLGIPQSSRDSFALLAANQ
IITIDLSDNLQKMVGLRNIAVHGYQALNLDIVIHVISHRLSDFEHFIKQIARYSDSQHL

Download         Length: 420 bp

>T141228 NZ_CP059900:174922-175269 [Tomitella sp. HY172]
ATGCTGCGCGGTGAGGTGCGGCTGGTCGATCTGGAGCCTGCTCGGGGAGGCGAGGCGGACAAGCGACGGCCGGCGGTCAT
CGTCAGCAATGACGGAGCCAACGCGACGGCGGCGCGCCTGGGCCGGGGAGTGGTGACGGTGGTGCCGGTGACCAGCAACA
CCGCTCGGGTGTTTCCGTTCCAGGTGCTCCTCGATACCGAGACCACCGGGCTGCGCATCGATGCGAAGGCGCAAGCGGAA
CAGGTGCGTTCCGTGGCGGTCGAACGGGTCGGACCGGCTATCGCACGACTGCCGGGGCCGGTGATGGGCGCAATCGACGA
TGCGCTCCGACTGCATCTGCAGCTGTAG

Antitoxin


Download         Length: 128 a.a.        Molecular weight: 14400.59 Da        Isoelectric Point: 4.7463

>AT141228 WP_161509016.1 NZ_CP045098:c2825735-2825352 [Pectobacterium carotovorum]
MFDKIVLTLKKQMPDIKIIYLFGSQATGNARADSDIDIAIMATRALDPVERWELSNQLAKEVGHDVDLIDLLQASTVLRM
EIVRNGKLLYDAETAAGEFEMTTLSMYQHLQKERADIIRSFNQDLKA

Download         Length: 384 bp

>AT141228 NZ_CP059900:174705-174935 [Tomitella sp. HY172]
ATGAAGATCAGCGTGAGTCTGCCGGAGGAGGACCTCGAGATCCTCGATACGTACATGCGCGAATCCGGGCTGCCGTCACG
TTCCTCGGCAATCCAGCGGGCGGTCAGGATGTTGCGGAATGTCGACCTGGAGGACGACTACGCGGCGGCGTGGAGTGAAT
GGGAGTCGTCCGGGGACGCCGGCGTGTGGGAGTCGGCCTCGGGGGACGGTCTCGCCGATGCTGCGCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References