Detailed information of TA system TA141226

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 2185732..2186224
• Replicon: chromosome
• Accession: NZ_CP045098
• Organism: Pectobacterium carotovorum strain ZM1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: GBN63_RS21315
• Protein ID: WP_275591534.1
• Coordinates: 2185732..2185983 (-)
• Length: 84 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: GBN63_RS09900
• Protein ID: WP_239768267.1
• Coordinates: 2185973..2186224 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GBN63_RS09865 (GBN63_09885)	2180871..2181653	-	783	WP_039507622.1	transporter substrate-binding domain-containing protein	-
GBN63_RS09870 (GBN63_09890)	2182023..2182565	-	543	WP_234932194.1	hypothetical protein	-
GBN63_RS09875 (GBN63_09895)	2182901..2183446	+	546	WP_203470387.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	-
GBN63_RS09880 (GBN63_09900)	2183430..2184347	+	918	WP_239768261.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	-
GBN63_RS09885 (GBN63_09905)	2184554..2185045	+	492	WP_239768263.1	DUF2559 family protein	-
GBN63_RS09890 (GBN63_09910)	2185038..2185634	+	597	WP_239768265.1	putative adenosine monophosphate-protein transferase Fic	-
GBN63_RS21315	2185732..2185983	-	252	WP_275591534.1	hypothetical protein	Toxin
GBN63_RS09900 (GBN63_09920)	2185973..2186224	-	252	WP_239768267.1	prevent-host-death protein	Antitoxin
GBN63_RS09905 (GBN63_09925)	2186354..2186823	+	470	Protein_1909	hypothetical protein	-
GBN63_RS09910 (GBN63_09930)	2186823..2187152	+	330	WP_226311589.1	DUF1493 family protein	-
GBN63_RS09920 (GBN63_09940)	2187848..2188330	-	483	WP_010282425.1	SsrA-binding protein SmpB	-
GBN63_RS09925 (GBN63_09945)	2188486..2188932	+	447	WP_104213420.1	type II toxin-antitoxin system RatA family toxin	-
GBN63_RS09930 (GBN63_09950)	2188913..2189203	+	291	WP_039470935.1	RnfH family protein	-
GBN63_RS09935 (GBN63_09955)	2189442..2189777	-	336	WP_239768268.1	outer membrane protein assembly factor BamE	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 9885.45 Da
• Isoelectric Point: 9.9585

>T141226 WP_275591534.1 NZ_CP045098:c2185983-2185732 [Pectobacterium carotovorum]
MSYKLEFEEHALKEFKKLGAPVREQFTKKLKEVLQHPYVPANRLHGMADCYKKFIKQPKTDYKRGQFSTRGYFVVQPIYQ
GDE

Nucleotide

• Length: 252 bp

>T141226 NZ_CP059898:2978893-2979153 [Streptomyces sp. M54]
GTGAAGTTCGTATGGGACCAGTCGTCCTGGGACGACTACGTCTGGTGGCAGAACCAGGACCGCAAGATCCTCAAGCGGAT
CAACGCGCTGCTCCAGGACATCGCCCGGAACGGCAACGAGGGGATGGGCAAGCCGGACCCCTTGAAGCACGGCTTCCACG
GATACTGGTCGCGGCGCATCACCGGCGAACACCGGCTCATCTACAAGGTGGGGGACGACGAGGTGCGCGTCGCGGCCTGC
CGTTACCACTACGGACGCTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9159.44 Da
• Isoelectric Point: 5.8233

>AT141226 WP_239768267.1 NZ_CP045098:c2186224-2185973 [Pectobacterium carotovorum]
MSVQPILANAAVSISDFKKSPNAALKEANGEPVAVLTNGHISGYYVSPETWEALADYQEDIELAKIARSRMKRKRVKVDL
DEL

Nucleotide

• Length: 252 bp

>AT141226 NZ_CP059898:2978645-2978896 [Streptomyces sp. M54]
ATGCGCACGATGACCTACACCGAGTCCCGCGCGAAGTACGCCGAGACTCTGAGCTCGGTCGTCGACGATCGCGAGGAGGT
CGTCGTCACGCGCGCCGGACACGAACCCGTGGTGATAGTGGCGCTCGACGAATACGAGTCCCTGAAGGAGACCGCGTACC
AGCTCAGGAGCCCCGAGAACGCACGCCGCCTGCTGGCCTCGATCGACCGCCTGGAGAACGGCGGCGGCACCGTGCGGGAG
CTCGCGGAGTGA