Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 1895582..1897280 Replicon chromosome
Accession NZ_CP045098
Organism Pectobacterium carotovorum strain ZM1

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag GBN63_RS08530 Protein ID WP_039539679.1
Coordinates 1895582..1896511 (-) Length 310 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag GBN63_RS08535 Protein ID WP_103161895.1
Coordinates 1896498..1897280 (-) Length 261 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GBN63_RS08495 1891754..1891891 - 138 WP_180890065.1 hypothetical protein -
GBN63_RS08500 (GBN63_08505) 1891967..1892188 + 222 Protein_1635 ATP-binding cassette domain-containing protein -
GBN63_RS08505 (GBN63_08510) 1892185..1892412 + 228 Protein_1636 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase -
GBN63_RS08510 (GBN63_08515) 1892516..1893085 + 570 WP_039540948.1 ribose 1,5-bisphosphokinase -
GBN63_RS08515 (GBN63_08520) 1893124..1893909 + 786 WP_205623291.1 phosphonate metabolism protein PhnP -
GBN63_RS08520 (GBN63_08525) 1894001..1894264 - 264 WP_010286385.1 DUF2798 domain-containing protein -
GBN63_RS08525 (GBN63_08530) 1894393..1895295 + 903 WP_039539675.1 LysR family transcriptional regulator -
GBN63_RS08530 (GBN63_08535) 1895582..1896511 - 930 WP_039539679.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
GBN63_RS08535 (GBN63_08540) 1896498..1897280 - 783 WP_103161895.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
GBN63_RS08540 (GBN63_08545) 1897609..1897782 + 174 WP_072012970.1 ash family protein -
GBN63_RS08545 (GBN63_08550) 1897746..1898207 + 462 WP_039470594.1 hypothetical protein -
GBN63_RS08550 (GBN63_08555) 1898204..1898413 + 210 WP_039470597.1 helix-turn-helix transcriptional regulator -
GBN63_RS08560 (GBN63_08565) 1898893..1899738 + 846 WP_239768090.1 AraC family transcriptional regulator -
GBN63_RS08565 (GBN63_08570) 1899774..1900364 + 591 WP_239768092.1 LysE family translocator -
GBN63_RS08570 (GBN63_08575) 1900361..1900936 - 576 WP_182813310.1 transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(14-262)

Antitoxin

Transcriptional regulator, AbiEi 3 antitoxin, Type IV TA system

(95-247)


Sequences

Toxin        


Download         Length: 310 a.a.        Molecular weight: 35176.61 Da        Isoelectric Point: 5.9099

>T141224 WP_039539679.1 NZ_CP045098:c1896511-1895582 [Pectobacterium carotovorum]
MDQRDIYARQVKLLMTALPYVAKEPCFALKGGTAINLFVQDFPRLSVDIDLVYQTFIDRDTDLIAIDDALMRITESLNGR
LGITAIQQENKADEKRIIVNTVDAQIKIEVSPVWRGLLLPPAEMPVCEQVEMEFGFTTMNVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPGLTRELFDGFLCYLAGHPRPIAELLAPNWDIARIATLYQQEFSGMTQHETSLESLLSVTTLLPQAL
RSHFTAQDKQFLLSYKQNTPDWSLYRYPDIQHLPAIRWKQHNLSALHAKNPAKFSTAVSKLEKVLEQRF

Download         Length: 930 bp

>T141224 NZ_CP059897:c1298471-1298184 [Ciceribacter thiooxidans]
ATGAGTGTTGGTCTTTCAGTTGAAGCGGAAGAGGACATTATCGCGATTGCCGAGCAAGGTGTCCGTATGTTCGGAGCAGG
CCAAGCAAAGCGCTACCACGATGAACTTTTCGCACTACTTGGTCTGTTAGCTGCCAATCCACGCATCGCGCGCGAACGGG
ATGAGATCAATCCACCCGTTAGAATTCATCCCTTCAAAGCGCATCTCGTTGTCTACCGAATCGAAGACGATGAAACAATT
TCTGTAATACGAGTTCGCCACGAGCATGAAGATTGGGCAAGTAATTGA

Antitoxin


Download         Length: 261 a.a.        Molecular weight: 29253.59 Da        Isoelectric Point: 9.1334

>AT141224 WP_103161895.1 NZ_CP045098:c1897280-1896498 [Pectobacterium carotovorum]
MTNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYVYVQNGWLRRIAHGVYCRTGREPDWVDAVYCLQTQWEKPVRVAGLT
SLALQGYSHYTELGKPQVWLTLPAYIKLPGWFAAFEPSATFVVLYTSGLSVDVMPFTTELKIGDRRLTGSVPELAAYEIA
SGVPTQISFEHADALFQGLHLLSPRKLQALLCASHSVKTNRVMLYLAQRNGHPYFQYLDKSGIETGAGKRQIVPGGWLEP
DYQITVPREFKSKGVENGSA

Download         Length: 783 bp

>AT141224 NZ_CP059897:c1298710-1298468 [Ciceribacter thiooxidans]
ATGGCCACGATGAATGTATCTCTTCCAGACCCGATGAAGGATTGGGTGGAGGCGCAGGCTAGGACCGGACGATATTCCAA
TGCCAGCGACTACGTGCGCGACCTGATCCGACGCGACCAGATGCGCAACGACAAGATTGCCGCCATGCAAAGCATCGTCG
ATGCCGGGCTCCGAAGTGGTGTTGGCATACGCTCAAAGGACGAACTCTTTGCTGAGGCGATGACTCGTGCCGGCGAGTCA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References