Detailed information of TA system TA141200

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): sdenTA/AbiEii(toxin)
• Location: 676715..678156
• Replicon: chromosome
• Accession: NZ_CP045097
• Organism: Pectobacterium carotovorum strain RC5297

Toxin (Protein)

• Gene name: sdenT
• Uniprot ID: A0A855MBQ9
• Locus tag: F9W95_RS02985
• Protein ID: WP_039296419.1
• Coordinates: 676715..677602 (-)
• Length: 296 a.a.

Antitoxin (Protein)

• Gene name: sdenA
• Uniprot ID: -
• Locus tag: F9W95_RS02990
• Protein ID: WP_107332130.1
• Coordinates: 677632..678156 (-)
• Length: 175 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
F9W95_RS02965 (F9W95_02985)	672706..673527	+	822	WP_103943069.1	M55 family metallopeptidase	-
F9W95_RS02970 (F9W95_02990)	673587..674534	+	948	WP_103943071.1	isoaspartyl peptidase/L-asparaginase	-
F9W95_RS02975 (F9W95_02995)	674739..675647	+	909	WP_039542502.1	LysR family transcriptional regulator	-
F9W95_RS02980 (F9W95_03000)	675746..676609	+	864	WP_010300687.1	YicC/YloC family endoribonuclease	-
F9W95_RS02985 (F9W95_03005)	676715..677602	-	888	WP_039296419.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
F9W95_RS02990 (F9W95_03010)	677632..678156	-	525	WP_107332130.1	hypothetical protein	Antitoxin
F9W95_RS02995 (F9W95_03015)	678476..680956	-	2481	WP_107332129.1	restriction endonuclease-like protein	-
F9W95_RS03000 (F9W95_03020)	680975..682867	-	1893	WP_240004559.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (39-265)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 296 a.a.
• Molecular weight: 34019.93 Da
• Isoelectric Point: 5.9876

>T141200 WP_039296419.1 NZ_CP045097:c677602-676715 [Pectobacterium carotovorum]
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIIDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFQPSAFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKISIVKEANRPDLPRQKMHIDVCAIPSFDIEKRPLINHYNIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIVWIKQRGIDLSKTLVEKKLTARQKQTEDFRQALSIQLAKLMSEDE
VRDDFNMEMSRFIPKQIKERTLDNPEYWAYVQGEVHAIASELLNDGTPKNPFNMG

Nucleotide

• Length: 888 bp

>T141200 NZ_CP059853:3567462-3567716 [Glutamicibacter nicotianae]
GTGCGGCTCGTCTGGGATCGGGCAGGATGGGACGACTACGTCCACTGGCAAACGGCCGACCGGCGCGTACTCAAGAGAGT
CAACACCTTGATCGAAGCATGCCTTCCGGATCCCTTCCAAGGGATTGGAAAGCCCGAACAGCTGAAATACGGGGCCTCCG
GCTCATGGTCCCGTCGGATTACCGACGAACACCGACTGGTCTACATCGTGATCGAAGAAGACTTGATCATCCTTCAAGCC
CGATACCACTATTGA

Antitoxin

Protein

• Length: 175 a.a.
• Molecular weight: 19352.48 Da
• Isoelectric Point: 9.0504

>AT141200 WP_107332130.1 NZ_CP045097:c678156-677632 [Pectobacterium carotovorum]
MAKSDELLNALAKSVNAGGGIHSVAELAFMQGVPCDSAFRKFLADCVKKGLLRRVVKGFYESVITPPEPETAIYKIIKKL
RSGVLNYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIEFTHTKKPVEQIAPNLYYDPDIKMYRAYKEQAIA
DLKHCQRNLHMLES

Nucleotide

• Length: 525 bp

>AT141200 NZ_CP059853:3567210-3567461 [Glutamicibacter nicotianae]
ATGTCCATCAGTGCAAGCGAAGCCCGCAAGACGCTCTTTCCATTGATTGAACAAGTCAACGATGATCGCCAAGCTGTCGA
AATCGTGTCACGCAAGGGAAATGCTGTTCTCATGGCAGCAGATGAATACGCAGCATGGCAAGAGACCGCGTACCTCTTCC
GCTCGCCAGCCAATGCCCGGCGGCTCTTGGATGCCTACGAACGTGCACGGTCAGGAATAACAGAGACCCACGAACTCGAC
TGGGACGAATAA

Structures

Toxin

• AlphaFold DB: A0A855MBQ9