Detailed information of TA system TA141197

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): slvAT/RES(toxin)
• Location: 14639..15594
• Replicon: plasmid pWSGX2
• Accession: NZ_CP045090
• Organism: Burkholderia glumae strain GX

Toxin (Protein)

• Gene name: slvT
• Uniprot ID: -
• Locus tag: GAS19_RS29490
• Protein ID: WP_017924249.1
• Coordinates: 15061..15594 (+)
• Length: 178 a.a.

Antitoxin (Protein)

• Gene name: slvA
• Uniprot ID: -
• Locus tag: GAS19_RS29485
• Protein ID: WP_017924250.1
• Coordinates: 14639..15064 (+)
• Length: 142 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GAS19_RS29465	10572..11651	+	1080	WP_012732706.1	ParB N-terminal domain-containing protein	-
GAS19_RS29470	11988..13319	+	1332	WP_012732707.1	hypothetical protein	-
GAS19_RS29475	13441..13767	+	327	WP_127913985.1	hypothetical protein	-
GAS19_RS29480	14306..14491	+	186	WP_148271081.1	hypothetical protein	-
GAS19_RS29485	14639..15064	+	426	WP_017924250.1	DUF2384 domain-containing protein	Antitoxin
GAS19_RS29490	15061..15594	+	534	WP_017924249.1	RES family NAD+ phosphorylase	Toxin
GAS19_RS29495	15755..15952	+	198	WP_127840952.1	hypothetical protein	-
GAS19_RS29500	16345..16572	+	228	WP_153479204.1	hypothetical protein	-
GAS19_RS29505	16642..16884	+	243	WP_124837682.1	hypothetical protein	-
GAS19_RS29510	17181..17522	+	342	WP_153479206.1	hypothetical protein	-
GAS19_RS29515	17525..19360	+	1836	WP_124837684.1	site-specific integrase	-
GAS19_RS29520	19445..19870	+	426	WP_012732713.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..105587	105587
	-	flank	IS/Tn	-	-	20344..20856	512

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (11-168)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 178 a.a.
• Molecular weight: 19131.69 Da
• Isoelectric Point: 5.1753

>T141197 WP_017924249.1 NZ_CP045090:15061-15594 [Burkholderia glumae]
MILTPLQDITAYRMHVPKWAVAPTSGAGAARAGGRANRVGTPALYLALEVATAVAEYQQLSPLLPPGTLVSYRVTATPVV
DFTGGFRADLWPPLWESFFCDWRRDWFNARIEPPSWVLGDEAIAAGAKGILFRSTQATGGTNLVLFVDQLGEGDRLDVHD
PAGALPRDQASWDGPSR

Nucleotide

• Length: 534 bp

>T141197 NZ_CP059851:c3178041-3177637 [Sandaracinobacter sp. M6]
TTGATCGTTGACACATCTGCCCTTCTGGCCATCATCTATGGTGAACCCGAAGCGGAATCCTTCGCTCGGCTGATTCTTGC
CGAATCGACGCCTGCGATGGCGGCGGTGACCTACCTGGAAGCGGCGCTGAAGCTGGACGGCGATCTGAAAAAGCCTTTGG
GCCCGCGTCTTGATGATACCATCGCAATGCTTGGTTTGGGGACTCTGTCGTTCACCGCAGAACATGCCCGACTGGCGCGA
CAGGCTGCCAAGCAATTCGGTAAGGGCAACCACCCCGCCAAACTGAACTTTGGTGATTGTATCGTCTATGCCACCGCCCA
GCTGGCGAATCGTCCGCTGCTGTTCAAGGGCAACGACTTTTCCCAGACCGATCTCGTTCCCGCGATTTCCAAGGACAATC
CATGA

Antitoxin

Protein

• Length: 142 a.a.
• Molecular weight: 14935.78 Da
• Isoelectric Point: 6.4664

>AT141197 WP_017924250.1 NZ_CP045090:14639-15064 [Burkholderia glumae]
MSTLAATRAPAAPAGGPAPASFDAFLSALREPDTAAPVLSARRYVAALNIDLQTLADQAHVHRNTVARAPQSASVQQFLR
EAIRVIRAATDLSGDVQRALFWYRNEPLAVFDYQTAETLVSAGRADDVVRYVASLEAGAAG

Nucleotide

• Length: 426 bp

>AT141197 NZ_CP059851:c3178310-3178038 [Sandaracinobacter sp. M6]
GTGGGACGACAGCTGAACATCAAGCATGACGACGCATGGGCGCTCGCGGAGCGGTTGAGCAGGAAAACGGGTGAGAGCAT
GACGGACGCTGTTGTCGTCAGCTTGCGCGAACGGCTGGCACGCCTCGAAGGCGCGCGCCAGGCGGAAGTTGAAGCGAAAC
TGGCTGCACTTCGGGCCATGGCCAGTTCCATACAGGCGGACTTGCGGCCCGACGCCATGACCGCAGAGCAATTCGATGCC
TGGATGTATGACGATCAAGGCCTGCCGCATTGA