Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 695917..696587 Replicon chromosome
Accession NZ_CP045073
Organism Paracoccus kondratievae strain BJQ0001

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag F8A10_RS14795 Protein ID WP_152367721.1
Coordinates 696153..696587 (+) Length 145 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag F8A10_RS14790 Protein ID WP_095641522.1
Coordinates 695917..696156 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F8A10_RS14765 691981..692325 - 345 WP_018000081.1 HNH endonuclease -
F8A10_RS14770 692465..692842 - 378 WP_152367717.1 helix-turn-helix domain-containing protein -
F8A10_RS14775 692835..693035 - 201 WP_193668321.1 hypothetical protein -
F8A10_RS14780 693371..695596 - 2226 WP_152367719.1 AAA family ATPase -
F8A10_RS14785 695593..695793 - 201 WP_152367720.1 hypothetical protein -
F8A10_RS14790 695917..696156 + 240 WP_095641522.1 Arc family DNA-binding protein Antitoxin
F8A10_RS14795 696153..696587 + 435 WP_152367721.1 PIN domain-containing protein Toxin
F8A10_RS14800 696584..697291 - 708 Protein_702 sigma-70 family RNA polymerase sigma factor -
F8A10_RS14805 697389..697622 - 234 WP_115754683.1 hypothetical protein -
F8A10_RS14810 697716..699878 - 2163 WP_152367722.1 hypothetical protein -
F8A10_RS14820 700212..700661 + 450 WP_152367723.1 DUF2924 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 681720..723061 41341


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-129)

Antitoxin

Arc-like DNA binding domain

(5-45)


Sequences

Toxin        


Download         Length: 145 a.a.        Molecular weight: 15417.70 Da        Isoelectric Point: 5.1875

>T141181 WP_152367721.1 NZ_CP045073:696153-696587 [Paracoccus kondratievae]
MIILDTNVVSETMKPVPEPRVIDWLNRQELSTLHLTTVSLAELRFGMARLEPGRRRDDFELRLERMLTEVFPGRVLGFDA
AAANAFGALVATAGRQGHAVSFADGAIAAIAAASGYPVASRDTAPFAAMGVKVVDPWGLPANEA

Download         Length: 435 bp

>T141181 NZ_CP059851:310080-311348 [Sandaracinobacter sp. M6]
ATGACGCGCACCCTCGATATCTGGTGGGACGGGCGCCTGGTAGGCCAGCTGACGCAGGACAAGCACGGTGAACTCGGCTT
CGCCTATGCGCGGGCTTGGCTTGACGATGAGGAGGCGCAGCCCTTGTCCGCCTCGCTGCCAAAGCGGGCGGAGCCGTTCA
CCCGCCGCGAATGCCGCCCGTATTTCAGCGGTCTCCTGCCGGAAGAAAGCCAGCGCGACGCCGCAGCTCAGGCACTCGGC
GTGTCGCGGGCCAATGATTTCGCCCTTCTTGATCGCCTCGGCGGCGATGTGGCGGGCGCGCTCCAGCTTCTGCCGCCCGG
CGAAGTACCAGCCACTCTTGCCCCCGATCAACGGCCAACCCCGCTTGACGATGCAGGGTTGATCCGGGTTCTGGATGCGC
TGCCCGTCCGACCATTGCTGGCTGGCGAGGAAGGCCTGCGTCTCTCTCTCGCTGGCGCGCAATCGAAGGTTCCGGTGGTT
CTGGTGGATGGCGTGGTGGCCTTGCCTGCGCCGGGCCAGCCGACGACGCATATTCTCAAGCCCCCGATATCCCGCTTCGC
GGCCACGACCGAGAACGAGGCGTTTGTGATGCGCCTTGCTGCCGCAATCGGCTTCGATGTCGCGCCGGTAGAAGTCCGCA
TCGTGCAGGATCGAACATTTCTGCTGGTCCAGCGCTATGACCGCGCCACCGGCGACGATGGCTTCGTGCGCCGGATCCAT
CAGGAGGATTTCTGCCAGGCGCTCGGCGTGCCGCCGGAGACCAAGTACGCCAGCGAGGGCGGCCCGACGTTCAAGGATTG
CTTCGCGCTGCTCCGCCGGGTCGTCGCAAGGCCCGCTGTCGATGTGCTGAAGCTCCTCGATGCCGTGATCTTCAATGTGA
TCGCCGGGAACGCCGACGCACATGGCAAGAATTTCTCGATCCTCTACGGCGCCGAAGGCCCACGCCTCGCCCCGCTCTAT
GATCTGCTCGCAACCGTTGCCTATCCCGATCTCTCGCCGAAATTCGCTATGAAGATCGGAAGGCGGGCGACGCTCGCGGA
ACTGGACGCCGATGGCTGGGCAGCGTTTGCGGCGGACGCGGGTGTCGGTCTGCCGCTGGTACGACGACGGATTGCAGAGA
TCAGCAAAGCTGTCCTTGAGAAGGCAACCGCCGTCGGAGCCGAGCTTTCGCGTCCAGGGTTGGACAGAACGGCTATTGCG
CGGTTTGCCGAGATGATCCGCGAGCGCGGCGAGCGCTGCGCTCTTACGGTCGCGGGACCTTCTCAATGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8662.88 Da        Isoelectric Point: 7.1682

>AT141181 WP_095641522.1 NZ_CP045073:695917-696156 [Paracoccus kondratievae]
VAQIVVRQIPDEVHRALKAQAAAHGRSAEAELREIIARAVLREGRPRAGDLMRGIWSGAAMDGFSVERDRTPVEPACFE

Download         Length: 240 bp

>AT141181 NZ_CP059851:309841-310083 [Sandaracinobacter sp. M6]
ATGGCCAGACGCAACCTCACCACCGCCGAGATCGGCGACATTGTTCGGACAACCCGCAAGGCCGCTGGCCTGCGGCAGGA
CGAGCTTGCCGGCGCAGCTGGCGTCGGCCTGCGCTTCATCGTCGATCTCGAAGCGGGCAAGGCGACCGCGCAGATCGGCA
AGACGCTTCAGGTCCTATCGGCGCTGGGCTGCTCGCTCGATATCACACCGCCGTCCGACCCCAAAGGAGCGCGGAAGGCA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References