Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 696348..696877 Replicon chromosome
Accession NZ_CP045072
Organism Paracoccus kondratievae strain BJQ0001

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag F8A10_RS03560 Protein ID WP_152366699.1
Coordinates 696348..696635 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag F8A10_RS03565 Protein ID WP_152366700.1
Coordinates 696632..696877 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F8A10_RS03520 692065..692283 - 219 WP_072461783.1 helix-turn-helix domain-containing protein -
F8A10_RS03525 692610..692933 + 324 WP_152366693.1 zinc ribbon domain-containing protein -
F8A10_RS03530 692930..693112 + 183 WP_028717528.1 hypothetical protein -
F8A10_RS03535 693109..693618 + 510 WP_152366694.1 hypothetical protein -
F8A10_RS03540 693615..693893 + 279 WP_152366695.1 hypothetical protein -
F8A10_RS03545 694035..694244 + 210 WP_152366696.1 hypothetical protein -
F8A10_RS03550 694572..695744 + 1173 WP_152366697.1 ATP-binding protein -
F8A10_RS03555 695966..696259 - 294 WP_152366698.1 hypothetical protein -
F8A10_RS03560 696348..696635 - 288 WP_152366699.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
F8A10_RS03565 696632..696877 - 246 WP_152366700.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
F8A10_RS03570 696982..698343 - 1362 WP_152366701.1 plasmid recombination protein -
F8A10_RS03575 698336..699433 - 1098 WP_152366702.1 hypothetical protein -
F8A10_RS03585 699902..700924 + 1023 WP_010398125.1 LacI family DNA-binding transcriptional regulator -
F8A10_RS03590 700971..701774 - 804 WP_152366703.1 type I methionyl aminopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-90)

Antitoxin

Antitoxin ParD

(4-72)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10638.11 Da        Isoelectric Point: 6.4738

>T141178 WP_152366699.1 NZ_CP045072:c696635-696348 [Paracoccus kondratievae]
MKALAFTVAATVDLEAIWDYTEGEWGLAQARRYVQELRDTCHALASGQGRGRPVDVRPGYLKCLSGSHVIFFRDLGDTLE
IVRILHGAQDVERHL

Download         Length: 288 bp

>T141178 NZ_CP059849:3680262-3680480 [Citrobacter freundii]
ATGTCCGATAAACCATTAACTAAAACAGATTATTTGATGCGCCTGCGACGTTGCCAGACTATTGATACGCTAGAGCGCGT
TATTGAAAAAAATAAATATGAATTGTCCGACAACGAACTGGCTGTATTTTACTCAGCAGCAGATCATCGCCTTGCTGAAT
TGACCATGAATAAGCTTTACGACAAGATTCCAACTTCTGTTTGGAAATTCATTCGCTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8810.88 Da        Isoelectric Point: 7.2038

>AT141178 WP_152366700.1 NZ_CP045072:c696877-696632 [Paracoccus kondratievae]
MSRNTSVSLGDHFVSFIDTQVKGGRYGSASDVVRAGLRLLEEHETKVKALQDALIAGEESGRAEGFDLDRFIARKMAGRN
A

Download         Length: 246 bp

>AT141178 NZ_CP059849:3679860-3680234 [Citrobacter freundii]
ATGGATGAATACTCACCCAAAAGACATGATATCGCGCAGCTTAAATTTCTCTGCGAAACTCTGTATCATGACTGTCTTGC
AAACCTTGAACAAAGTAACCATGGCTGGGTTAATGACCCTACCTCTGCAACCAGCTTGCAGCTCAATGAACTGATAGAGC
ATATTGCAACCTTCGCACTTAATTATAAAATTAAGTACAATGAGGACAATAAGCTGATCGCGCAGATAGATGAATACCTG
GATGACACTTTTATGTTGTTCAGCAGTTATGGTATTAATACGCAGGATCTGCAGAAATGGCGGAAGTCAGGTAATCGACT
GTTTCGCTGTTTTGTCAATGCCACCAGGGCTAATCCTGTTAGTTTGTCTTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References