Detailed information of TA system TA141158

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 233426..233961
• Replicon: plasmid pLG26p2
• Accession: NZ_CP045061
• Organism: Salmonella enterica subsp. enterica serovar Muenchen strain LG26

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: SMLG26_RS01490
• Protein ID: WP_097361649.1
• Coordinates: 233674..233961 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: SMLG26_RS01485
• Protein ID: WP_057394760.1
• Coordinates: 233426..233677 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SMLG26_RS01455	229052..229597	+	546	WP_153789535.1	phospholipase D family protein	-
SMLG26_RS01460	229735..229992	+	258	WP_057395075.1	replication regulatory protein RepA	-
SMLG26_RS01465	230224..230298	+	75	WP_071529947.1	RepA leader peptide Tap	-
SMLG26_RS01470	230291..231307	+	1017	WP_097361647.1	replication initiation protein	-
SMLG26_RS01475	232183..232575	-	393	WP_097361648.1	nuclear transport factor 2 family protein	-
SMLG26_RS01480	233066..233339	-	274	Protein_255	recombinase family protein	-
SMLG26_RS01485	233426..233677	+	252	WP_057394760.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
SMLG26_RS01490	233674..233961	+	288	WP_097361649.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
SMLG26_RS01495	233966..234196	+	231	WP_057394395.1	hypothetical protein	-
SMLG26_RS01500	234352..234594	+	243	WP_057394396.1	hypothetical protein	-
SMLG26_RS01505	234712..234948	-	237	WP_176193362.1	hypothetical protein	-
SMLG26_RS25930	236071..236826	+	756	WP_176193363.1	hypothetical protein	-
SMLG26_RS01515	236876..237406	-	531	WP_071497240.1	colicin immunity protein Cui	-
SMLG26_RS01520	237465..237896	-	432	WP_057393438.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..270863	270863

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 12322.73 Da
• Isoelectric Point: 12.7777

>T141158 WP_097361649.1 NZ_CP045061:233674-233961 [Salmonella enterica subsp. enterica serovar Muenchen]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKK

Nucleotide

• Length: 288 bp

>T141158 NZ_CP059840:2784114-2784221 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTTGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 10784.64 Da
• Isoelectric Point: 12.7191

>AT141158 WP_057394760.1 NZ_CP045061:233426-233677 [Salmonella enterica subsp. enterica serovar Muenchen]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKK

Nucleotide

• Length: 252 bp

>AT141158 NZ_CP059840:c2784064-2784001 [Escherichia coli]
TCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTATACCTCTCAACGTGCGGGGGTTTTCT